biostudies-literatureUnknown11Wang N<h4>Objective</h4>The current research aimed to examine how dietary intake and rare earth elements may affect the development of tongue cancer.<h4>Methods</h4>The serum levels of 10 rare earth elements (REEs) in 171 cases and 171 healthy matched controls were measured by inductively coupled plasma mass spectrometry (ICP-MS). The conditional logistic regression was used to examine the relationship between dietary intake, serum levels of 10 REEs, and tongue cancer. Mediation effect and multiplicative interaction analysis were then performed to estimate the potential contribution of REEs in dietary intake associated with tongue cancer.<h4>Results</h4>Compared with the control group, patients with tongue cancer consumed significantly less fish, seafood, fruit, green leafy vegetables, and non-gFrontiers in public health1058013https://www.ebi.ac.uk/biostudies/studies/S-EPMC10169683biostudies-literatureThe role of rare earth elements and dietary intake in tongue cancer: a mediation analysis in southeast China.PMC10169683Qiu YWang NGao BShi BXie MChen FChen YLin LHe BLiu FfalseThe role of rare earth elements and dietary intake in tongue cancer: a mediation analysis in southeast China.<h4>Objective</h4>The current research aimed to examine how dietary intake and rare earth elements may affect the development of tongue cancer.<h4>Methods</h4>The serum levels of 10 rare earth elements (REEs) in 171 cases and 171 healthy matched controls were measured by inductively coupled plasma mass spectrometry (ICP-MS). The conditional logistic regression was used to examine the relationship between dietary intake, serum levels of 10 REEs, and tongue cancer. Mediation effect and multiplicative interaction analysis were then performed to estimate the potential contribution of REEs in dietary intake associated with tongue cancer.<h4>Results</h4>Compared with the control group, patients with tongue cancer consumed significantly less fish, seafood, fruit, green leafy vegetables, and non-g2023-01-01T00:00:00Z20232025-04-18T15:13:15.2Z2025-04-07T01:47:26.824ZS-EPMC101696833718170710.3389/fpubh.2023.1058013