biostudies-literatureLiu GShenzhen International Science and Technology Cooperation ProjectChina National Postdoctoral Program for Innovative TalentsGuangdong Basic and Applied Basic Research FoundationGuangdong Provincial Key Laboratory of Advanced BiomaterialsShenzhen Science and Technology Program151https://www.ebi.ac.uk/biostudies/studies/S-EPMC10170720biostudies-literatureUnknown21(1)<h4>Background</h4>Photothermal therapy (PTT) in the second near-infrared (NIR-II) window has attracted extensive attention due to the benefits in high maximum permissible exposure and penetration depth. Current photothermal agents generally show a broadband absorption accompanied by a gradual attenuation of absorption in the NIR-II window, leading to poor effect of PTT. It remains a great challenge to gain photothermal agents with strong and characteristic absorption in NIR-II regions. To overcome this problem, based on carbon dots (CDs)-mediated growth strategy, we proposed a simple and feasible approach to prepare plasmonic gold nanodendrites (AuNDs) with NIR-II absorption to enhance the therapeutic effect of PTT.<h4>Results</h4>By rationally regulating the size and branch length of AuNJournal of nanobiotechnologyCarbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy.PMC10170720GJHZ202007310952080252022B1212010003BX202202152023A1515012658RCYX20221008092946108Yin YLi HZha MWang SMu JWu RLi KSong JLiu GShi YfalseCarbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy.<h4>Background</h4>Photothermal therapy (PTT) in the second near-infrared (NIR-II) window has attracted extensive attention due to the benefits in high maximum permissible exposure and penetration depth. Current photothermal agents generally show a broadband absorption accompanied by a gradual attenuation of absorption in the NIR-II window, leading to poor effect of PTT. It remains a great challenge to gain photothermal agents with strong and characteristic absorption in NIR-II regions. To overcome this problem, based on carbon dots (CDs)-mediated growth strategy, we proposed a simple and feasible approach to prepare plasmonic gold nanodendrites (AuNDs) with NIR-II absorption to enhance the therapeutic effect of PTT.<h4>Results</h4>By rationally regulating the size and branch length of AuN2023-01-01T00:00:00Z2023 May2025-04-22T14:44:41.722Z2025-04-06T01:06:13.881ZS-EPMC101707203716146710.1186/s12951-023-01887-2