biostudies-literatureGrosicki GJNCATS NIH HHSNational Heart, Lung, and Blood InstituteNHLBI NIH HHSNIHBPGeorgia Southern University102718https://www.ebi.ac.uk/biostudies/studies/S-EPMC10172749biostudies-literatureUnknown63A complex interplay of social, lifestyle, and physiological factors contribute to Black Americans having the highest blood pressure (BP) in America. One potential contributor to Black adult's higher BP may be reduced nitric oxide (NO) bioavailability. Therefore, we sought to determine whether augmenting NO bioavailability with acute beetroot juice (BRJ) supplementation would reduce resting BP and cardiovascular reactivity in Black and White adults, but to a greater extent in Black adults. A total of 18 Black and 20 White (∼equal split by biological sex) young adults completed this randomized, placebo-controlled (nitrate (NO₃^-)-depleted BRJ), crossover design study. We measured heart rate, brachial and central BP, and arterial stiffness (via pulse wave velocity) at resRedox biologyAcute beetroot juice reduces blood pressure in young Black and White males but not females.PMC1017274945,78,84,85K01HL14799878–83K01 HL147998R15HL165325R15 HL165325UL1 TR003096K01 HL16077279,80,82,84,86,87K01HL160772UL1TR003096Cross BLSanchez SORicart KRobinson ATBryan ABlumenburg WTLincoln ZRWatso JCFlatt AAPatel RPGrosicki GJLinder BAVondrasek JDChall AfalseAcute beetroot juice reduces blood pressure in young Black and White males but not females.A complex interplay of social, lifestyle, and physiological factors contribute to Black Americans having the highest blood pressure (BP) in America. One potential contributor to Black adult's higher BP may be reduced nitric oxide (NO) bioavailability. Therefore, we sought to determine whether augmenting NO bioavailability with acute beetroot juice (BRJ) supplementation would reduce resting BP and cardiovascular reactivity in Black and White adults, but to a greater extent in Black adults. A total of 18 Black and 20 White (∼equal split by biological sex) young adults completed this randomized, placebo-controlled (nitrate (NO₃^-)-depleted BRJ), crossover design study. We measured heart rate, brachial and central BP, and arterial stiffness (via pulse wave velocity) at res2023-01-01T00:00:00Z2023 Jul2026-05-28T08:23:59.381Z2025-04-05T21:09:19.235ZS-EPMC101727493712092810.1016/j.redox.2023.102718