{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pike S"],"funding":["NCI NIH HHS"],"pagination":["194-202"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10176191"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["We describe a rare case of ocular surface squamous neoplasia (OSSN) with intraocular spread after excisional biopsy which presented as a postoperative anterior chamber (A/C) opacity, initially thought to be a hypopyon. A 60-year-old female with history of a right (OD) conjunctival mass involving the cornea, surgically excised and diagnosed as OSSN, presented 2 months postoperatively with an A/C opacity concerning for infection. The patient was prescribed prednisolone acetate and ofloxacin drops postoperatively; topical chemotherapy was not given. When the opacity did not respond to 3 weeks of topical treatment, they were referred to an ocular oncologist for management. Intraoperative records from biopsy were unavailable; use of cryotherapy is unknown. On presentation, the patient had reduc"],"journal":["Case reports in ophthalmology"],"pubmed_title":["Intraocular Spread of Ocular Surface Squamous Neoplasia Presenting as a Postoperative Anterior Chamber Opacity after Excisional Biopsy."],"pmcid":["PMC10176191"],"funding_grant_id":["K08 CA232344"],"pubmed_authors":["Berry JL","In GK","Sibug Saber ME","Pike S","Engelhard SB","Matthew AJ"],"additional_accession":[]},"is_claimable":false,"name":"Intraocular Spread of Ocular Surface Squamous Neoplasia Presenting as a Postoperative Anterior Chamber Opacity after Excisional Biopsy.","description":"We describe a rare case of ocular surface squamous neoplasia (OSSN) with intraocular spread after excisional biopsy which presented as a postoperative anterior chamber (A/C) opacity, initially thought to be a hypopyon. A 60-year-old female with history of a right (OD) conjunctival mass involving the cornea, surgically excised and diagnosed as OSSN, presented 2 months postoperatively with an A/C opacity concerning for infection. The patient was prescribed prednisolone acetate and ofloxacin drops postoperatively; topical chemotherapy was not given. When the opacity did not respond to 3 weeks of topical treatment, they were referred to an ocular oncologist for management. Intraoperative records from biopsy were unavailable; use of cryotherapy is unknown. On presentation, the patient had reduc","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan-Dec","modification":"2025-04-04T14:12:48.234Z","creation":"2025-04-04T14:12:48.234Z"},"accession":"S-EPMC10176191","cross_references":{"pubmed":["37187670"],"doi":["10.1159/000530335"]}}