{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lei X"],"funding":["Natural Science Foundation of Hebei Province","National Natural Science Foundation of China","National Key Research and Development Program of China"],"pagination":["7926"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10178733"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(9)"],"pubmed_abstract":["It is well established that potassium (K<sup>+</sup>) is an essential nutrient for wheat (<i>Triticum aestivum</i> L.) growth and development. Several microRNAs (miRNAs), including miR166, are reportedly vital roles related to plant growth and stress responses. In this study, a K<sup>+</sup> starvation-responsive miRNA (miR166d) was identified, which showed increased expression in the roots of wheat seedlings exposed to low-K<sup>+</sup> stress. The overexpression of miR166d considerably increased the tolerance of transgenic Arabidopsis plants to K<sup>+</sup> deprivation treatment. Furthermore, disrupting miR166d expression via virus-induced gene silencing (VIGS) adversely affected wheat adaptation to low-K<sup>+</sup> stress. Additionally, miR166d directly targeted the calcium-dependent "],"journal":["International journal of molecular sciences"],"pubmed_title":["The miR166d/<i>TaCPK7-D</i> Signaling Module Is a Critical Mediator of Wheat (<i>Triticum aestivum</i> L.) Tolerance to K<sup>+</sup> Deficiency."],"pmcid":["PMC10178733"],"funding_grant_id":["2022YFD1200204","31901539","C2021204066"],"pubmed_authors":["Yang X","Xu K","Zhao S","Wu N","Xiao K","Lei X","Chen M","Sun R","Zhang S","Zhao Y"],"additional_accession":[]},"is_claimable":false,"name":"The miR166d/<i>TaCPK7-D</i> Signaling Module Is a Critical Mediator of Wheat (<i>Triticum aestivum</i> L.) Tolerance to K<sup>+</sup> Deficiency.","description":"It is well established that potassium (K<sup>+</sup>) is an essential nutrient for wheat (<i>Triticum aestivum</i> L.) growth and development. Several microRNAs (miRNAs), including miR166, are reportedly vital roles related to plant growth and stress responses. In this study, a K<sup>+</sup> starvation-responsive miRNA (miR166d) was identified, which showed increased expression in the roots of wheat seedlings exposed to low-K<sup>+</sup> stress. The overexpression of miR166d considerably increased the tolerance of transgenic Arabidopsis plants to K<sup>+</sup> deprivation treatment. Furthermore, disrupting miR166d expression via virus-induced gene silencing (VIGS) adversely affected wheat adaptation to low-K<sup>+</sup> stress. Additionally, miR166d directly targeted the calcium-dependent ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Apr","modification":"2025-04-26T17:26:09.805Z","creation":"2025-04-06T15:28:54.22Z"},"accession":"S-EPMC10178733","cross_references":{"pubmed":["37175632"],"doi":["10.3390/ijms24097926"]}}