{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Voronov IS"],"funding":["Russian Science Foundation"],"pagination":["3945"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10180310"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["28(9)"],"pubmed_abstract":["Pentacyclic triterpenoids (PCTs), which possess a number of bioactive properties, are considered one of the most important classes of secondary plant metabolites. Their chromatographic determination in plant biomass is complicated by the need to separate a large number of structurally similar compounds belonging to several classes that differ greatly in polarity (monools, diols, and triterpenic acids). This study proposes a rapid, sensitive, and low-cost method for the simultaneous quantification of ten PCTs (3<i>β</i>-taraxerol, lupeol, <i>β</i>-amyrin, <i>α</i>-amyrin, betulin, erythrodiol, uvaol, betulinic, oleanolic, and ursolic acids) by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) using porous graphitic carbon (Hypercarb) as a stationary phase capable "],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Determination of Pentacyclic Triterpenoids in Plant Biomass by Porous Graphitic Carbon Liquid Chromatography-Tandem Mass Spectrometry."],"pmcid":["PMC10180310"],"funding_grant_id":["21-73-00291"],"pubmed_authors":["Voronov IS","Ul'yanovskii NV","Faleva AV","Falev DI","Kosyakov DS"],"additional_accession":[]},"is_claimable":false,"name":"Determination of Pentacyclic Triterpenoids in Plant Biomass by Porous Graphitic Carbon Liquid Chromatography-Tandem Mass Spectrometry.","description":"Pentacyclic triterpenoids (PCTs), which possess a number of bioactive properties, are considered one of the most important classes of secondary plant metabolites. Their chromatographic determination in plant biomass is complicated by the need to separate a large number of structurally similar compounds belonging to several classes that differ greatly in polarity (monools, diols, and triterpenic acids). This study proposes a rapid, sensitive, and low-cost method for the simultaneous quantification of ten PCTs (3<i>β</i>-taraxerol, lupeol, <i>β</i>-amyrin, <i>α</i>-amyrin, betulin, erythrodiol, uvaol, betulinic, oleanolic, and ursolic acids) by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) using porous graphitic carbon (Hypercarb) as a stationary phase capable ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-18T15:12:24.416Z","creation":"2025-04-07T01:50:40.882Z"},"accession":"S-EPMC10180310","cross_references":{"pubmed":["37175355"],"doi":["10.3390/molecules28093945"]}}