{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Huang J"],"funding":["the Yichun Dahaigui Life Science Co., Ltd","the Hubei Hongshan Laboratory","the National Natural Science Foundation of China"],"pagination":["430-441"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10186138"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(5)"],"pubmed_abstract":["Early weaned piglets suffer from oxidative stress and enteral infection, which usually results in gut microbial dysbiosis, serve diarrhea, and even death. Rice bran oil (RBO), a polyphenol-enriched by-product of rice processing, has been shown to have antioxidant and anti-inflammatory properties both in vivo and in vitro. Here, we ascertained the proper RBO supplementation level, and subsequently determined its effects on lipopolysaccharide (LPS)-induced intestinal dysfunction in weaned piglets. A total of 168 piglets were randomly allocated into four groups of seven replicates (42 piglets each group, (21±1) d of age, body weight (7.60±0.04) kg, and half males and half females) and were given basal diet (Ctrl) or basal diet supplemented with 0.01% (mass fraction) RBO (RBO1), 0.02% RBO (RBO"],"journal":["Journal of Zhejiang University. Science. B"],"pubmed_title":["Rice bran oil supplementation protects swine weanlings against diarrhea and lipopolysaccharide challenge."],"pmcid":["PMC10186138"],"funding_grant_id":["32230099 and 31925037","2021hszd018","20222ZDH04093"],"pubmed_authors":["Ma L","Huang J","Xu B","Chen Y","Qin W","Sun H","Zhao J","Yan X","Jing F","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"Rice bran oil supplementation protects swine weanlings against diarrhea and lipopolysaccharide challenge.","description":"Early weaned piglets suffer from oxidative stress and enteral infection, which usually results in gut microbial dysbiosis, serve diarrhea, and even death. Rice bran oil (RBO), a polyphenol-enriched by-product of rice processing, has been shown to have antioxidant and anti-inflammatory properties both in vivo and in vitro. Here, we ascertained the proper RBO supplementation level, and subsequently determined its effects on lipopolysaccharide (LPS)-induced intestinal dysfunction in weaned piglets. A total of 168 piglets were randomly allocated into four groups of seven replicates (42 piglets each group, (21±1) d of age, body weight (7.60±0.04) kg, and half males and half females) and were given basal diet (Ctrl) or basal diet supplemented with 0.01% (mass fraction) RBO (RBO1), 0.02% RBO (RBO","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-25T22:30:43.643Z","creation":"2025-04-06T09:03:33.396Z"},"accession":"S-EPMC10186138","cross_references":{"pubmed":["37190892"],"doi":["10.1631/jzus.b2200565","10.1631/jzus.B2200565"]}}