{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(5)"],"submitter":["Liu W"],"pubmed_abstract":["Anthocyanins are valuable compounds in red-fleshed apples. The MdMYB10 transcription factor is an important regulator of the anthocyanin synthesis pathway. However, other transcription factors are key components of the complex network controlling anthocyanin synthesis and should be more thoroughly characterized. In this study, we used a yeast-based screening technology to identify MdNAC1 as a transcription factor that positively regulates anthocyanin synthesis. The overexpression of <i>MdNAC1</i> in apple fruits and calli significantly promoted the accumulation of anthocyanins. In binding experiments, we demonstrated that MdNAC1 combines with the bZIP-type transcription factor <i>MdbZIP23</i> to activate the transcription of <i>MdMYB10</i> and <i>MdUFGT</i>. Our analyses also indicated tha"],"journal":["Horticulture research"],"pagination":["uhad049"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10186271"],"repository":["biostudies-literature"],"pubmed_title":["The ABA-induced NAC transcription factor MdNAC1 interacts with a bZIP-type transcription factor to promote anthocyanin synthesis in red-fleshed apples."],"pmcid":["PMC10186271"],"pubmed_authors":["Gu T","Fang H","Wang N","Yu L","Li Z","Zhang Z","Mei Z","Zou Q","Chen X","Zhang S","Wang Y","Liu W"],"additional_accession":[]},"is_claimable":false,"name":"The ABA-induced NAC transcription factor MdNAC1 interacts with a bZIP-type transcription factor to promote anthocyanin synthesis in red-fleshed apples.","description":"Anthocyanins are valuable compounds in red-fleshed apples. The MdMYB10 transcription factor is an important regulator of the anthocyanin synthesis pathway. However, other transcription factors are key components of the complex network controlling anthocyanin synthesis and should be more thoroughly characterized. In this study, we used a yeast-based screening technology to identify MdNAC1 as a transcription factor that positively regulates anthocyanin synthesis. The overexpression of <i>MdNAC1</i> in apple fruits and calli significantly promoted the accumulation of anthocyanins. In binding experiments, we demonstrated that MdNAC1 combines with the bZIP-type transcription factor <i>MdbZIP23</i> to activate the transcription of <i>MdMYB10</i> and <i>MdUFGT</i>. Our analyses also indicated tha","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-05T09:10:26.082Z","creation":"2025-04-05T09:10:26.082Z"},"accession":"S-EPMC10186271","cross_references":{"pubmed":["37200839"],"doi":["10.1093/hr/uhad049"]}}