{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(3)"],"submitter":["Kim CR"],"pubmed_abstract":["Prompt administration of first-aid drugs can save lives during medical emergencies such as anaphylaxis and hypoglycemia. However, this is often performed by needle self-injection, which is not easy for patients under emergency conditions. Therefore, we propose an implantable device capable of on-demand administration of first-aid drugs (i.e., the implantable device with a magnetically rotating disk [iMRD]), such as epinephrine and glucagon, via a noninvasive simple application of the magnet from the outside skin (i.e., the external magnet). The iMRD contained a disk embedded with a magnet, as well as multiple drug reservoirs that were sealed with a membrane, which was designed to rotate at a precise angle only when the external magnet was applied. During this rotation, the membrane on a de"],"journal":["Bioengineering & translational medicine"],"pagination":["e10479"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10189441"],"repository":["biostudies-literature"],"pubmed_title":["Implantable device with magnetically rotating disk for needle-free administrations of emergency drug."],"pmcid":["PMC10189441"],"pubmed_authors":["Cho YC","Lee C","Kim CR","Choy YB","Ji HB","Kim SN","Kim MJ","Min CH","Han JH"],"additional_accession":[]},"is_claimable":false,"name":"Implantable device with magnetically rotating disk for needle-free administrations of emergency drug.","description":"Prompt administration of first-aid drugs can save lives during medical emergencies such as anaphylaxis and hypoglycemia. However, this is often performed by needle self-injection, which is not easy for patients under emergency conditions. Therefore, we propose an implantable device capable of on-demand administration of first-aid drugs (i.e., the implantable device with a magnetically rotating disk [iMRD]), such as epinephrine and glucagon, via a noninvasive simple application of the magnet from the outside skin (i.e., the external magnet). The iMRD contained a disk embedded with a magnet, as well as multiple drug reservoirs that were sealed with a membrane, which was designed to rotate at a precise angle only when the external magnet was applied. During this rotation, the membrane on a de","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-05T10:55:27.057Z","creation":"2025-04-05T10:55:27.057Z"},"accession":"S-EPMC10189441","cross_references":{"pubmed":["37206225"],"doi":["10.1002/btm2.10479"]}}