biostudies-literatureUnknown329(19)G-CHF Investigators<h4>Importance</h4>Most epidemiological studies of heart failure (HF) have been conducted in high-income countries with limited comparable data from middle- or low-income countries.<h4>Objective</h4>To examine differences in HF etiology, treatment, and outcomes between groups of countries at different levels of economic development.<h4>Design, setting, and participants</h4>Multinational HF registry of 23 341 participants in 40 high-income, upper-middle-income, lower-middle-income, and low-income countries, followed up for a median period of 2.0 years.<h4>Main outcomes and measures</h4>HF cause, HF medication use, hospitalization, and death.<h4>Results</h4>Mean (SD) age of participants was 63.1 (14.9) years, and 9119 (39.1%) were female. The most common cause of HF was ischemic heart diseasJAMA1650-1661https://www.ebi.ac.uk/biostudies/studies/S-EPMC10189564biostudies-literatureGlobal Variations in Heart Failure Etiology, Management, and Outcomes.PMC10189564Dutra OPFedorov SRusso GVarghese KPozdnyakov YLonn EReis GRoses JLRasmussen MAvezum AHernandes MEKovalkova NDelarche NClausell NMirek-Bryniarska ELund LHClovis NQuiroz FEljach JEVJourda FSizova ZMcMurray JJVGaggin HAlla FOgah OKitchen TMarcassa CXu JNegi PMwita JCEzekowitz JFloras JStahl FMoreira IYufereva YMoe GChmielinski AMondo CTamdja ADAbib ERouleau JLManon GECarreno EMMYusubova AChaudley GBhatta YCruz JMendoza JLALopez JPiepoli MMeda JRDonnelly PHertting KMeier MAWei FRoss HSolkiewicz MDuma NAirhart SWujkowski MSantiago EGupta RPiepiorka MGulati MHominal MABuelvas JMohan BLozada HGRoy ALonnberg IColette SBai XKorol MAi FCastro-Montes ECarrasco SZhu JGoussot SToma MGoloskokova VLugero CHage CScopigni FOwsiak MFeuzeu SANVenturi FMehta RKenizou DKayani AMGulizia MKhetan ANobre FKinsara ACadena Bonfanti ABoulestreav RSaidu HSharma DGou JWGrinvalds APavanello RChen YCosmi FZaidman CJChen XOsipova IGomez-Mesa JEPaniagua Martin MJDada FATKostis JAdler FBan'Haka HMKataraihya JWeiss CJano GGafarov VKanenda SUllah Jan UMalhotra VGarcia ALawand STantchou CJaramillo MSZieroth SAbdullakutty JBarton JJathappa NJiang HFomekong TGLanas FPina IGulec SAlghalayini KElSayed APiccinni GIvan SSilva-Cardoso JErtl GWolf AGuillot JPTartiere JMWhellan DPerez FNielsen GDuran RGRacine NTrujillo FMoeketsi KJia ZChandra SPogosova NNyanga ABobadilla BSchellong SBazargani NPedersen MMurillo NCavusoglu YMaier SMakubi ADrexler MPrado AMaia LNHagenow AMinan GMaggioni APOliveira LAnderson KBruder OOliveira MAlasmari SO'Donnell MBranch KRJuneman ECaballero EBHamou KHMwakalukwa BAlHabib KFDamasceno ALiang TMurthy SAbah JPMphahlele MJMoreno GSKadel CFuat AArimie RTemizhan AFox KJhund PDans ALVelez MSCzerski TBazan SZYilmaz MBMonem SJin WAnzules NGosse PSandoval JEdwards TSharma SKBednarski JSia YTLong FPCAcar DRZheng TNalwa WMurphy AVogt RMielniczuk LStasiwski AWiggers HHabeeb WLindholm CJMahrholdt HTirador LZeyad MHeckman GAsotra SKassim YMacKinnon IStoerk TIsakova SMiklaszewicz BVilamajo OGQin SOrlandini AKalokola FCelik AVega MThorvaldsen TSenechal MAndriyevska SSousa AMbugua ESalbieva ARatsela ADzudie ADokainish HMinelli CKazmi KMoccetti TBudaj ASliwa KZhou WBalasubramanian KCeron JACetin HEOJungmair WParkhomenko ASudnik WZuelta INgongang FADPeng JIto WWu JYusuf SMorales DThomas BMProbstfield JLepage SNagele HThulin JKaraye KLeong DKarna SArden CChillo PAndrade AWang TKragholm KGniot JNdjebet JWang XBarasa FVillani GQNtsekhe MLopez JACTan HTan GMoriarty ASogaard PSwiggum ESergey ZFloderer NZVereschuk LSkorski MBott MCDe La Espriella RGarrido Bravo IBayes-Genis AThew SAl-Mulla AAGao XZalizna YDe Salazar DIMKisenge PRojas DGMcCready TWitherow FYonga GDe Souza WKSBGopalan RG-CHF InvestigatorsStork SGislason GSulit DHintze RD'Orazio SVoronkov LMaurice KDuarte YCFrisinghelli AZapata GMcKelvie REvangelista LKLuo HYMcadam BBuitrago ACursack GPoponina TLiang XWNganou-Gnindjio CNKouam CKPanov DAbang SMJoseph PSweitzer NSmith SLopez-Jaramillo PWittlinger TCymerman KWagdy Shaker KTournoux FAnsa VfalseGlobal Variations in Heart Failure Etiology, Management, and Outcomes.<h4>Importance</h4>Most epidemiological studies of heart failure (HF) have been conducted in high-income countries with limited comparable data from middle- or low-income countries.<h4>Objective</h4>To examine differences in HF etiology, treatment, and outcomes between groups of countries at different levels of economic development.<h4>Design, setting, and participants</h4>Multinational HF registry of 23 341 participants in 40 high-income, upper-middle-income, lower-middle-income, and low-income countries, followed up for a median period of 2.0 years.<h4>Main outcomes and measures</h4>HF cause, HF medication use, hospitalization, and death.<h4>Results</h4>Mean (SD) age of participants was 63.1 (14.9) years, and 9119 (39.1%) were female. The most common cause of HF was ischemic heart diseas2023-01-01T00:00:00Z2023 May2025-04-04T19:15:56.853Z2025-04-04T19:15:56.853ZS-EPMC101895643719170410.1001/jama.2023.5942