biostudies-literatureUnknown14(19)Nan JHerein, we disclose a novel reorganization/cycloaddition between two imine units catalyzed by In(OTf)₃ Lewis acid that differs from the well-known [4 + 2] cycloaddition version <i>via</i> the Povarov reaction. By means of this unprecedented imine chemistry, a collection of synthetically useful dihydroacridines has been synthesized. Notably, the obtained products give rise to a series of structurally novel and fine-tuneable acridinium photocatalysts, offering a heuristic paradigm for synthesis and efficiently facilitating several encouraging dihydrogen coupling reactions.Chemical science5160-5166https://www.ebi.ac.uk/biostudies/studies/S-EPMC10189902biostudies-literatureIn(OTf)₃-catalyzed reorganization/cycloaddition of two imine units and subsequent modular assembly of acridinium photocatalysts.PMC10189902Luan XHuang GMa YLiu SNan JWang JfalseIn(OTf)₃-catalyzed reorganization/cycloaddition of two imine units and subsequent modular assembly of acridinium photocatalysts.Herein, we disclose a novel reorganization/cycloaddition between two imine units catalyzed by In(OTf)₃ Lewis acid that differs from the well-known [4 + 2] cycloaddition version <i>via</i> the Povarov reaction. By means of this unprecedented imine chemistry, a collection of synthetically useful dihydroacridines has been synthesized. Notably, the obtained products give rise to a series of structurally novel and fine-tuneable acridinium photocatalysts, offering a heuristic paradigm for synthesis and efficiently facilitating several encouraging dihydrogen coupling reactions.2023-01-01T00:00:00Z2023 May2025-04-21T22:40:40.247Z2025-04-05T18:52:28.561ZS-EPMC101899023720640910.1039/d3sc00163f