{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Parera Olm I"],"funding":["Dutch Research Council (NWO)"],"pagination":["83"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10189929"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(1)"],"pubmed_abstract":["<h4>Background</h4>Dilute ethanol streams generated during fermentation of biomass or syngas can be used as feedstocks for the production of higher value products. In this study, we describe a novel synthetic microbial co-culture that can effectively upgrade dilute ethanol streams to odd-chain carboxylic acids (OCCAs), specifically valerate and heptanoate. The co-culture consists of two strict anaerobic microorganisms: Anaerotignum neopropionicum, a propionigenic bacterium that ferments ethanol, and Clostridium kluyveri, well-known for its chain-elongating metabolism. In this co-culture, A. neopropionicum grows on ethanol and CO<sub>2</sub> producing propionate and acetate, which are then utilised by C. kluyveri for chain elongation with ethanol as the electron donor.<h4>Results</h4>A co-c"],"journal":["Biotechnology for biofuels and bioproducts"],"pubmed_title":["Upgrading dilute ethanol to odd-chain carboxylic acids by a synthetic co-culture of Anaerotignum neopropionicum and Clostridium kluyveri."],"pmcid":["PMC10189929"],"funding_grant_id":["ALWGK.2016.029"],"pubmed_authors":["Sousa DZ","Parera Olm I"],"additional_accession":[]},"is_claimable":false,"name":"Upgrading dilute ethanol to odd-chain carboxylic acids by a synthetic co-culture of Anaerotignum neopropionicum and Clostridium kluyveri.","description":"<h4>Background</h4>Dilute ethanol streams generated during fermentation of biomass or syngas can be used as feedstocks for the production of higher value products. In this study, we describe a novel synthetic microbial co-culture that can effectively upgrade dilute ethanol streams to odd-chain carboxylic acids (OCCAs), specifically valerate and heptanoate. The co-culture consists of two strict anaerobic microorganisms: Anaerotignum neopropionicum, a propionigenic bacterium that ferments ethanol, and Clostridium kluyveri, well-known for its chain-elongating metabolism. In this co-culture, A. neopropionicum grows on ethanol and CO<sub>2</sub> producing propionate and acetate, which are then utilised by C. kluyveri for chain elongation with ethanol as the electron donor.<h4>Results</h4>A co-c","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-27T01:38:47.126Z","creation":"2025-04-06T18:20:34.433Z"},"accession":"S-EPMC10189929","cross_references":{"pubmed":["37194097"],"doi":["10.1186/s13068-023-02336-w"]}}