{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Deng Y"],"funding":["Non-profit Central Research Institution Fund of Chinese Academy of Medical Sciences","National Natural Science Foundation of China","Sanming Project of Medicine in Shenzhen","CAMS Innovation Fund for Medical Sciences (CIFMS), China"],"pagination":["131"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10190004"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["Background
To explore the clinical prognostic utility of the preoperative cholesterol-to-lymphocyte ratio (CLR) in outcomes for colorectal cancer liver metastasis (CRLM) patients receiving simultaneous resection of the primary lesion and liver metastases.Methods
A total of 444 CRLM patients receiving simultaneous resections were enrolled. The optimal cut-off value for CLR was determined using the highest Youden's index. Patients were divided into the CLR < 3.06 group and the CLR≥3.06 group. Propensity score matching analysis (PSM) and the inverse probability of treatment weighting (IPTW) method were conducted to eliminate bias between the two groups. The outcomes included short-term outcomes and long-term outcomes. Kaplan-Meier curves and log-rank tests were used to analyse"],"journal":["BMC surgery"],"pubmed_title":["An elevated preoperative cholesterol-to-lymphocyte ratio predicts unfavourable outcomes in colorectal cancer liver metastasis patients receiving simultaneous resections: a retrospective study."],"pmcid":["PMC10190004"],"funding_grant_id":["No. 81972311, 82141127","No. 2019PT310026","No. SZSM202011010","No. 2021-I2M-1-066"],"pubmed_authors":["Bi X","Chen Q","Li Z","Chen J","Huang Z","Zhang Y","Cai J","Zhao J","Deng Y","Zhao H"],"additional_accession":[]},"is_claimable":false,"name":"An elevated preoperative cholesterol-to-lymphocyte ratio predicts unfavourable outcomes in colorectal cancer liver metastasis patients receiving simultaneous resections: a retrospective study.","description":"Background
To explore the clinical prognostic utility of the preoperative cholesterol-to-lymphocyte ratio (CLR) in outcomes for colorectal cancer liver metastasis (CRLM) patients receiving simultaneous resection of the primary lesion and liver metastases.Methods
A total of 444 CRLM patients receiving simultaneous resections were enrolled. The optimal cut-off value for CLR was determined using the highest Youden's index. Patients were divided into the CLR < 3.06 group and the CLR≥3.06 group. Propensity score matching analysis (PSM) and the inverse probability of treatment weighting (IPTW) method were conducted to eliminate bias between the two groups. The outcomes included short-term outcomes and long-term outcomes. Kaplan-Meier curves and log-rank tests were used to analyse","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-22T14:50:25.524Z","creation":"2025-04-06T01:06:45.544Z"},"accession":"S-EPMC10190004","cross_references":{"pubmed":["37194000"],"doi":["10.1186/s12893-023-01988-7"]}}