{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jacobs BM"],"funding":["Barts Charity","Medical Research Council","Aims2Cure","Multiple Sclerosis Society"],"pagination":["e071656"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10193065"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(5)"],"pubmed_abstract":["Purpose
Genetic studies of multiple sclerosis (MS) susceptibility and severity have focused on populations of European ancestry. Studying MS genetics in other ancestral groups is necessary to determine the generalisability of these findings. The genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis (ADAMS) project aims to gather genetic and phenotypic data on a large cohort of ancestrally-diverse individuals with MS living in the UK.Participants
Adults with self-reported MS from diverse ancestral backgrounds. Recruitment is via clinical sites, online (https://app.mantal.co.uk/adams) or the UK MS Register. We are collecting demographic and phenotypic data using a baseline questionnaire and subsequent healthcare record linkage. We"],"journal":["BMJ open"],"pubmed_title":["ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK."],"pmcid":["PMC10193065"],"funding_grant_id":["MGU0364","MR/V028766/1"],"pubmed_authors":["Giovannoni G","Murray R","Gran B","Tallantyre E","Tuite Dalton K","Mein CA","Patel S","Brooke J","Spilker C","Middleton R","Rhule N","Sacre E","Hassan-Smith G","Pogreban T","Begum T","Papachatzaki M","Evangelou N","Sawcer S","Silber E","Nandoskar A","Arun T","O'Malley M","Kaimal R","Ford HL","Tanveer R","George K","Mattoscio M","Peter M","Gumus S","Wozniak E","Bezzina EL","Breedon J","Shamji R","Antoine V","Schalk L","Morris H","Bellfield R","Kreft KL","Raj S","Sellers C","Boulton R","Noyce AJ","Dunne A","Mitchell S","Dobson R","Quinn O","Jacobs BM","Uzochukwu E","Rashid W","Hoque S","Visentin E","Vinod N","Rog D","Scalfari A","Bradley J","Harris J","Brown TL"],"additional_accession":[]},"is_claimable":false,"name":"ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK.","description":"Purpose
Genetic studies of multiple sclerosis (MS) susceptibility and severity have focused on populations of European ancestry. Studying MS genetics in other ancestral groups is necessary to determine the generalisability of these findings. The genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis (ADAMS) project aims to gather genetic and phenotypic data on a large cohort of ancestrally-diverse individuals with MS living in the UK.Participants
Adults with self-reported MS from diverse ancestral backgrounds. Recruitment is via clinical sites, online (https://app.mantal.co.uk/adams) or the UK MS Register. We are collecting demographic and phenotypic data using a baseline questionnaire and subsequent healthcare record linkage. We","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2026-06-03T21:29:00.268Z","creation":"2025-06-28T03:06:10.266Z"},"accession":"S-EPMC10193065","cross_references":{"pubmed":["37197821"],"doi":["10.1136/bmjopen-2023-071656"]}}