{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Molinas M"],"funding":["Swiss National Science Foundation","European Research Council"],"pagination":["7537-7546"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10193582"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["57(19)"],"pubmed_abstract":["The biological reduction of soluble U(VI) complexes to form immobile U(IV) species has been proposed to remediate contaminated sites. It is well established that multiheme <i>c</i>-type cytochromes (MHCs) are key mediators of electron transfer to aqueous phase U(VI) complexes for bacteria such as <i>Shewanella oneidensis</i> MR-1. Recent studies have confirmed that the reduction proceeds via a first electron transfer forming pentavalent U(V) species that readily disproportionate. However, in the presence of the stabilizing aminocarboxylate ligand, dpaea<sup>2-</sup> (dpaeaH<sub>2</sub>═bis(pyridyl-6-methyl-2-carboxylate)-ethylamine), biologically produced U(V) persisted in aqueous solution at pH 7. We aim to pinpoint the role of MHC in the reduction of U(V)-dpaea and to establish the mecha"],"journal":["Environmental science & technology"],"pubmed_title":["Mechanism of Reduction of Aqueous U(V)-dpaea and Solid-Phase U(VI)-dpaea Complexes: The Role of Multiheme <i>c</i>-Type Cytochromes."],"pmcid":["PMC10193582"],"funding_grant_id":["200021E-164209","725675"],"pubmed_authors":["Meibom KL","Mazzanti M","Bernier-Latmani R","Faizova R","Molinas M"],"additional_accession":[]},"is_claimable":false,"name":"Mechanism of Reduction of Aqueous U(V)-dpaea and Solid-Phase U(VI)-dpaea Complexes: The Role of Multiheme <i>c</i>-Type Cytochromes.","description":"The biological reduction of soluble U(VI) complexes to form immobile U(IV) species has been proposed to remediate contaminated sites. It is well established that multiheme <i>c</i>-type cytochromes (MHCs) are key mediators of electron transfer to aqueous phase U(VI) complexes for bacteria such as <i>Shewanella oneidensis</i> MR-1. Recent studies have confirmed that the reduction proceeds via a first electron transfer forming pentavalent U(V) species that readily disproportionate. However, in the presence of the stabilizing aminocarboxylate ligand, dpaea<sup>2-</sup> (dpaeaH<sub>2</sub>═bis(pyridyl-6-methyl-2-carboxylate)-ethylamine), biologically produced U(V) persisted in aqueous solution at pH 7. We aim to pinpoint the role of MHC in the reduction of U(V)-dpaea and to establish the mecha","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-21T22:43:23.418Z","creation":"2025-04-05T18:54:33.142Z"},"accession":"S-EPMC10193582","cross_references":{"pubmed":["37133831"],"doi":["10.1021/acs.est.3c00666"]}}