biostudies-literatureUnknown17Chen X<h4>Background and purpose</h4>Aneurysm wall enhancement (AWE) in high-resolution magnetic resonance imaging (HR-MRI) is a potential biomarker for evaluating unstable aneurysms. Fusiform intracranial aneurysms (FIAs) frequently have a complex and curved structure. We aimed to develop a new three-dimensional (3D) aneurysmal wall enhancement (AWE) characterization method to enable comprehensive FIA evaluation and to investigate the ability of 3D-AWE to predict symptomatic FIA.<h4>Methods</h4>We prospectively recruited patients with unruptured FIAs and received 3 T HR-MRI imaging from September 2017 to January 2019. 3D models of aneurysms and parent arteries were generated. Boundaries of the FIA were determined using 3D vessel diameter measurements. D_max was the greatest diameter iFrontiers in neuroscience1171946https://www.ebi.ac.uk/biostudies/studies/S-EPMC10196058biostudies-literatureThree-dimensional aneurysm wall enhancement in fusiform intracranial aneurysms is associated with aneurysmal symptoms.PMC10196058Sui BXu PBai XZhao XLiu XPeng FXia JLi ZXu BHe XLiu AChen XNiu HDuan YfalseThree-dimensional aneurysm wall enhancement in fusiform intracranial aneurysms is associated with aneurysmal symptoms.<h4>Background and purpose</h4>Aneurysm wall enhancement (AWE) in high-resolution magnetic resonance imaging (HR-MRI) is a potential biomarker for evaluating unstable aneurysms. Fusiform intracranial aneurysms (FIAs) frequently have a complex and curved structure. We aimed to develop a new three-dimensional (3D) aneurysmal wall enhancement (AWE) characterization method to enable comprehensive FIA evaluation and to investigate the ability of 3D-AWE to predict symptomatic FIA.<h4>Methods</h4>We prospectively recruited patients with unruptured FIAs and received 3 T HR-MRI imaging from September 2017 to January 2019. 3D models of aneurysms and parent arteries were generated. Boundaries of the FIA were determined using 3D vessel diameter measurements. D_max was the greatest diameter i2023-01-01T00:00:00Z20232025-04-27T04:25:47.395Z2025-04-06T19:07:08.612ZS-EPMC101960583721438610.3389/fnins.2023.1171946