{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Han CJ"],"funding":["Women&apos;s Health Initiative"],"pagination":["e0286058"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10198480"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(5)"],"pubmed_abstract":["<h4>Purpose</h4>Colorectal cancer (CRC) survivors often experience long-term symptoms after cancer treatments. But gastrointestinal (GI) symptom experiences are under-investigated in CRC survivors. We described persistent GI symptoms after cancer treatments in female CRC survivors and assessed GI symptoms' risk and life-impact factors.<h4>Methods</h4>A cross-sectional study utilized data from the Women's Health Initiative (WHI) Life and Longevity After Cancer (LILAC) study that recruited postmenopausal women. Correlation analyses and multivariable linear regression models were used.<h4>Results</h4>CRC survivors after cancer treatments were included (N = 413, mean age 71.2 years old, mean time since diagnosis = 8.1 years). 81% of CRC survivors experienced persistent GI symptoms. Bloating/ga"],"journal":["PloS one"],"pubmed_title":["Factors associated with long-term gastrointestinal symptoms in colorectal cancer survivors in the women's health initiatives (WHI study)."],"pmcid":["PMC10198480"],"funding_grant_id":["75N92021D00001, 75N92021D00002, 75N92021D00003, 75N92021D00004, 75N92021D00005."],"pubmed_authors":["Reding KW","Han CJ","Yung R","Kalady MF","Paskett ED","Greenlee H"],"additional_accession":[]},"is_claimable":false,"name":"Factors associated with long-term gastrointestinal symptoms in colorectal cancer survivors in the women's health initiatives (WHI study).","description":"<h4>Purpose</h4>Colorectal cancer (CRC) survivors often experience long-term symptoms after cancer treatments. But gastrointestinal (GI) symptom experiences are under-investigated in CRC survivors. We described persistent GI symptoms after cancer treatments in female CRC survivors and assessed GI symptoms' risk and life-impact factors.<h4>Methods</h4>A cross-sectional study utilized data from the Women's Health Initiative (WHI) Life and Longevity After Cancer (LILAC) study that recruited postmenopausal women. Correlation analyses and multivariable linear regression models were used.<h4>Results</h4>CRC survivors after cancer treatments were included (N = 413, mean age 71.2 years old, mean time since diagnosis = 8.1 years). 81% of CRC survivors experienced persistent GI symptoms. Bloating/ga","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-05T10:54:34.487Z","creation":"2025-04-05T10:54:34.487Z"},"accession":"S-EPMC10198480","cross_references":{"pubmed":["37205667"],"doi":["10.1371/journal.pone.0286058"]}}