biostudies-literatureNordhjem BJTBørnecancerfondenKræftens BekæmpelseHelsefondenNovo Nordisk Fondene070534https://www.ebi.ac.uk/biostudies/studies/S-EPMC10201232biostudies-literatureUnknown13(5)<h4>Introduction</h4>The aim of this research is to investigate young cancer patients' cognitive functioning and the underlying neurobiological mechanisms when cognitive functions are impaired. The MyBrain protocol is a multidisciplinary study that investigates cancer-related cognitive impairment in children, adolescents and young adults, combining neuropsychology, cognitive neuroscience and cellular neuroscience. The study is exploratory with a wide focus on trajectories of cognitive functions from diagnosis to the end of treatment and into survivorship.<h4>Methods and analysis</h4>Prospective longitudinal study including patients diagnosed with non-brain cancers at age 7-29 years. Each patient is paired with a control matched on age and social circle.<h4>Primary objective</h4>Evaluation BMJ openProtocol for a prospective, longitudinal study of cognitive impairment in young patients with cancer: a multidisciplinary neuroscience approach (MyBrain).PMC10201232R260-A152212021-744218-B-02762020-6785NNF21OC0072440Tjornlund MHjerming MNordhjem BJTHjalgrim LLPappot HKjær TWThomsen BLfalseProtocol for a prospective, longitudinal study of cognitive impairment in young patients with cancer: a multidisciplinary neuroscience approach (MyBrain).<h4>Introduction</h4>The aim of this research is to investigate young cancer patients' cognitive functioning and the underlying neurobiological mechanisms when cognitive functions are impaired. The MyBrain protocol is a multidisciplinary study that investigates cancer-related cognitive impairment in children, adolescents and young adults, combining neuropsychology, cognitive neuroscience and cellular neuroscience. The study is exploratory with a wide focus on trajectories of cognitive functions from diagnosis to the end of treatment and into survivorship.<h4>Methods and analysis</h4>Prospective longitudinal study including patients diagnosed with non-brain cancers at age 7-29 years. Each patient is paired with a control matched on age and social circle.<h4>Primary objective</h4>Evaluation 2023-01-01T00:00:00Z2023 May2026-05-28T17:51:03.957Z2025-04-04T14:29:48.541ZS-EPMC102012323720214310.1136/bmjopen-2022-070534