biostudies-literatureBoobier SRoyal Academy of EngineeringEngineering and Physical Sciences Research Council2895-2901https://www.ebi.ac.uk/biostudies/studies/S-EPMC10207257biostudies-literatureUnknown63(10)An Electronic Laboratory Notebook (ELN) combining features, including data archival, collaboration tools, and green and sustainability metrics for organic chemistry, is presented. AI4Green is a web-based application, available as open-source code and free to use. It offers the core functionality of an ELN, namely, the ability to store reactions securely and share them among different members of a research team. As users plan their reactions and record them in the ELN, green and sustainable chemistry is encouraged by automatically calculating green metrics and color-coding hazards, solvents, and reaction conditions. The interface links a database constructed from data extracted from PubChem, enabling the automatic collation of information for reactions. The application's design facilitates Journal of chemical information and modelingAI4Green: An Open-Source ELN for Green and Sustainable Chemistry.PMC10207257CiET2021_17EP/S035990/1Handley CMDavies JCBoobier SHirst JDDerbenev INfalseAI4Green: An Open-Source ELN for Green and Sustainable Chemistry.An Electronic Laboratory Notebook (ELN) combining features, including data archival, collaboration tools, and green and sustainability metrics for organic chemistry, is presented. AI4Green is a web-based application, available as open-source code and free to use. It offers the core functionality of an ELN, namely, the ability to store reactions securely and share them among different members of a research team. As users plan their reactions and record them in the ELN, green and sustainable chemistry is encouraged by automatically calculating green metrics and color-coding hazards, solvents, and reaction conditions. The interface links a database constructed from data extracted from PubChem, enabling the automatic collation of information for reactions. The application's design facilitates 2023-01-01T00:00:00Z2023 May2025-04-04T09:59:08.49Z2025-04-04T09:59:08.49ZS-EPMC102072573715534610.1021/acs.jcim.3c00306