biostudies-literaturePetrone IFundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)8733https://www.ebi.ac.uk/biostudies/studies/S-EPMC10218364biostudies-literatureUnknown24(10)Some transcripts that are not translated into proteins can be encoded by the mammalian genome. Long noncoding RNAs (lncRNAs) are noncoding RNAs that can function as decoys, scaffolds, and enhancer RNAs and can regulate other molecules, including microRNAs. Therefore, it is essential that we obtain a better understanding of the regulatory mechanisms of lncRNAs. In cancer, lncRNAs function through several mechanisms, including important biological pathways, and the abnormal expression of lncRNAs contributes to breast cancer (BC) initiation and progression. BC is the most common type of cancer among women worldwide and has a high mortality rate. Genetic and epigenetic alterations that can be regulated by lncRNAs may be related to early events of BC progression. Ductal carcinoma in situ (DCIS)International journal of molecular sciencesEpigenetic Alterations in DCIS Progression: What Can lncRNAs Teach Us?PMC10218364SEI-260003/001147/2020.Santos ECDPetrone IBinato RAbdelhay EfalseEpigenetic Alterations in DCIS Progression: What Can lncRNAs Teach Us?Some transcripts that are not translated into proteins can be encoded by the mammalian genome. Long noncoding RNAs (lncRNAs) are noncoding RNAs that can function as decoys, scaffolds, and enhancer RNAs and can regulate other molecules, including microRNAs. Therefore, it is essential that we obtain a better understanding of the regulatory mechanisms of lncRNAs. In cancer, lncRNAs function through several mechanisms, including important biological pathways, and the abnormal expression of lncRNAs contributes to breast cancer (BC) initiation and progression. BC is the most common type of cancer among women worldwide and has a high mortality rate. Genetic and epigenetic alterations that can be regulated by lncRNAs may be related to early events of BC progression. Ductal carcinoma in situ (DCIS)2023-01-01T00:00:00Z2023 May2026-05-13T14:48:05.684Z2025-04-04T19:30:09.425ZS-EPMC102183643724007710.3390/ijms24108733