biostudies-literatureUnknown13(5)Lewandrowski KUPain generator-based lumbar spinal decompression surgery is the backbone of modern spine care. In contrast to traditional image-based medical necessity criteria for spinal surgery, assessing the severity of neural element encroachment, instability, and deformity, staged management of common painful degenerative lumbar spine conditions is likely to be more durable and cost-effective. Targeting validated pain generators can be accomplished with simplified decompression procedures associated with lower perioperative complications and long-term revision rates. In this perspective article, the authors summarize the current concepts of successful management of spinal stenosis patients with modern transforaminal endoscopic and translaminar minimally invasive spinal surgery techniques. They represJournal of personalized medicine710https://www.ebi.ac.uk/biostudies/studies/S-EPMC10219192biostudies-literaturePersonalized Interventional Surgery of the Lumbar Spine: A Perspective on Minimally Invasive and Neuroendoscopic Decompression for Spinal Stenosis.PMC10219192Sea Aramayo JMDe Carvalho PSTde Sa Carneiro GDuchen Rodriguez LMOn Behalf Of Teams/Organizations/InstitutionsGomez FACristante AFPark JYRamirez CMeves RDowling AYang HValerio Pascua JEDefino HMoyano JSanchez JASKim HSYamamoto VYeung AGomez Silva IMRamirez Leon JFCarelli LEMenezes CMLim KTMeng BKateb BAmaral RZeng JGarcia ALewandrowski KURodriguez Garcia MMartinez EELorio MPFiorelli RKAfalsePersonalized Interventional Surgery of the Lumbar Spine: A Perspective on Minimally Invasive and Neuroendoscopic Decompression for Spinal Stenosis.Pain generator-based lumbar spinal decompression surgery is the backbone of modern spine care. In contrast to traditional image-based medical necessity criteria for spinal surgery, assessing the severity of neural element encroachment, instability, and deformity, staged management of common painful degenerative lumbar spine conditions is likely to be more durable and cost-effective. Targeting validated pain generators can be accomplished with simplified decompression procedures associated with lower perioperative complications and long-term revision rates. In this perspective article, the authors summarize the current concepts of successful management of spinal stenosis patients with modern transforaminal endoscopic and translaminar minimally invasive spinal surgery techniques. They repres2023-01-01T00:00:00Z2023 Apr2025-04-04T19:30:23.001Z2025-04-04T19:30:23.001ZS-EPMC102191923724088010.3390/jpm13050710