{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pataskar A"],"funding":["European Research Council","KWF Kankerbestrijding"],"pagination":["502"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10239192"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Background</h4>Cancer immunotherapy is implemented by identifying antigens that are presented on the cell surface of cancer cells and illicit T-cell response (Schumacher and Schreiber, Science 348:69-74, 2015; Waldman et al., Nat Rev Immunol 20:651-668, 2020; Zhang et al., Front Immunol 12:672,356, 2021b). Classical candidates of such antigens are the peptides resulting from genetic alterations and are named \"neoantigen\" (Schumacher and Schreiber, Science 348:69-74, 2015). Neoantigens have been widely catalogued across several human cancer types (Tan et al., Database (Oxford) 2020;2020b; Vigneron et al., Cancer Immun 13:15, 2013; Yi et al., iScience 24:103,107, 2021; Zhang et al., BMC Bioinformatics 22:40, 2021a). Recently, a new class of inducible antigens has been identified, namely "],"journal":["BMC cancer"],"pubmed_title":["ABPEPserver: a web application for documentation and analysis of substitutants."],"pmcid":["PMC10239192"],"funding_grant_id":["832844","13647"],"pubmed_authors":["Montenegro Navarro J","Agami R","Pataskar A"],"additional_accession":[]},"is_claimable":false,"name":"ABPEPserver: a web application for documentation and analysis of substitutants.","description":"<h4>Background</h4>Cancer immunotherapy is implemented by identifying antigens that are presented on the cell surface of cancer cells and illicit T-cell response (Schumacher and Schreiber, Science 348:69-74, 2015; Waldman et al., Nat Rev Immunol 20:651-668, 2020; Zhang et al., Front Immunol 12:672,356, 2021b). Classical candidates of such antigens are the peptides resulting from genetic alterations and are named \"neoantigen\" (Schumacher and Schreiber, Science 348:69-74, 2015). Neoantigens have been widely catalogued across several human cancer types (Tan et al., Database (Oxford) 2020;2020b; Vigneron et al., Cancer Immun 13:15, 2013; Yi et al., iScience 24:103,107, 2021; Zhang et al., BMC Bioinformatics 22:40, 2021a). Recently, a new class of inducible antigens has been identified, namely ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jun","modification":"2025-04-04T23:07:46.875Z","creation":"2025-04-04T23:07:46.875Z"},"accession":"S-EPMC10239192","cross_references":{"pubmed":["37270525"],"doi":["10.1186/s12885-023-10970-8"]}}