{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Mohammadkhani R"],"pubmed_abstract":["Considerable scientific evidence suggests that the intrauterine environment plays a crucial role in determining the long-term health of offspring. The present study aims to investigate the effects of high-intensity interval training in maternal rats before and during pregnancy on the antioxidant status, mitochondrial gene expression, and anxiety-like behavior of their offspring. A total of thirty-two female rats were assigned to four maternal groups based on the timing of exercise: before pregnancy, before and during pregnancy, during pregnancy, and sedentary. The female and male offspring were allocated to groups that matched their mothers' exercise regimen. Anxiety-like behavior in the offspring was evaluated using the open-field and elevated plus-maze tests. Our findings indicate that m"],"journal":["Frontiers in physiology"],"pagination":["1117666"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10242028"],"repository":["biostudies-literature"],"pubmed_title":["Maternal high-intensity interval training as a suitable approach for offspring's heart protection in rat: evidence from oxidative stress and mitochondrial genes."],"pmcid":["PMC10242028"],"pubmed_authors":["Komaki A","Karimi SA","Heidarisasan S","Salehi I","Mohammadkhani R","Behzad M"],"additional_accession":[]},"is_claimable":false,"name":"Maternal high-intensity interval training as a suitable approach for offspring's heart protection in rat: evidence from oxidative stress and mitochondrial genes.","description":"Considerable scientific evidence suggests that the intrauterine environment plays a crucial role in determining the long-term health of offspring. The present study aims to investigate the effects of high-intensity interval training in maternal rats before and during pregnancy on the antioxidant status, mitochondrial gene expression, and anxiety-like behavior of their offspring. A total of thirty-two female rats were assigned to four maternal groups based on the timing of exercise: before pregnancy, before and during pregnancy, during pregnancy, and sedentary. The female and male offspring were allocated to groups that matched their mothers' exercise regimen. Anxiety-like behavior in the offspring was evaluated using the open-field and elevated plus-maze tests. Our findings indicate that m","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-19T07:23:47.221Z","creation":"2025-04-19T07:23:47.221Z"},"accession":"S-EPMC10242028","cross_references":{"pubmed":["37288431"],"doi":["10.3389/fphys.2023.1117666"]}}