biostudies-literatureUnknown6(4)Stone GW<h4>Background</h4>Reshaping the dilated left ventricle using a surgically implanted papillary muscle sling has been shown to provide long-term improvement in cardiac function compared to annuloplasty alone in patients with systolic heart failure. A papillary muscle sling which can be implanted via a transcatheter approach has the potential to make this treatment more widely available to patients.<h4>Methods</h4>The Vsling transcatheter papillary muscle sling device was evaluated in a chronic animal model (sacrificed at 30 and 90 days), in a simulator, and in a human cadaver.<h4>Results</h4>The Vsling device was successfully implanted in 10 pigs, 6 simulator procedures, and 1 human cadaver. Procedure complexity and device usability were rated as reasonable or better by 6 interventional carStructural heart : the journal of the Heart Team100075https://www.ebi.ac.uk/biostudies/studies/S-EPMC10242562biostudies-literatureDescription, Feasibility, and Histological Assessment of the Vsling, a Novel Transcatheter Ventricular Repair Device.PMC10242562Stone GWManash BNeustadter DSievert HVirmani RShaler LWfalseDescription, Feasibility, and Histological Assessment of the Vsling, a Novel Transcatheter Ventricular Repair Device.<h4>Background</h4>Reshaping the dilated left ventricle using a surgically implanted papillary muscle sling has been shown to provide long-term improvement in cardiac function compared to annuloplasty alone in patients with systolic heart failure. A papillary muscle sling which can be implanted via a transcatheter approach has the potential to make this treatment more widely available to patients.<h4>Methods</h4>The Vsling transcatheter papillary muscle sling device was evaluated in a chronic animal model (sacrificed at 30 and 90 days), in a simulator, and in a human cadaver.<h4>Results</h4>The Vsling device was successfully implanted in 10 pigs, 6 simulator procedures, and 1 human cadaver. Procedure complexity and device usability were rated as reasonable or better by 6 interventional car2022-01-01T00:00:00Z2022 Aug2025-04-19T07:21:16.085Z2024-12-04T08:14:13.203ZS-EPMC102425623728833110.1016/j.shj.2022.100075