{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Adams RL"],"funding":["Medical Research Council"],"pubmed_abstract":["<h4>Background</h4>Copy number variants (CNVs) have been associated with the risk of schizophrenia, autism and intellectual disability. However, little is known about their spectrum of psychopathology in adulthood.<h4>Methods</h4>We investigated the psychiatric phenotypes of adult CNV carriers and compared probands, who were ascertained through clinical genetics services, with carriers who were not. One hundred twenty-four adult participants (age 18-76), each bearing one of 15 rare CNVs, were recruited through a variety of sources including clinical genetics services, charities for carriers of genetic variants, and online advertising. A battery of psychiatric assessments was used to determine psychopathology.<h4>Results</h4>The frequencies of psychopathology were consistently higher for th"],"journal":["Psychological medicine"],"pagination":["1-8"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10244007"],"repository":["biostudies-literature"],"pubmed_title":["Psychopathology in adults with copy number variants."],"pmcid":["PMC10244007"],"funding_grant_id":["MR/L010305/1"],"pubmed_authors":["Adams RL","Owen MJ","Baird A","Williams N","Linden DEJ","Linden SC","Hall J","van den Bree MBM","Smith J"],"additional_accession":[]},"is_claimable":false,"name":"Psychopathology in adults with copy number variants.","description":"<h4>Background</h4>Copy number variants (CNVs) have been associated with the risk of schizophrenia, autism and intellectual disability. However, little is known about their spectrum of psychopathology in adulthood.<h4>Methods</h4>We investigated the psychiatric phenotypes of adult CNV carriers and compared probands, who were ascertained through clinical genetics services, with carriers who were not. One hundred twenty-four adult participants (age 18-76), each bearing one of 15 rare CNVs, were recruited through a variety of sources including clinical genetics services, charities for carriers of genetic variants, and online advertising. A battery of psychiatric assessments was used to determine psychopathology.<h4>Results</h4>The frequencies of psychopathology were consistently higher for th","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-19T08:11:26.384Z","creation":"2025-04-19T08:11:26.384Z"},"accession":"S-EPMC10244007","cross_references":{"pubmed":["35144709"],"doi":["10.1017/S0033291721005201"]}}