biostudies-literatureUnknown38(3)Hamana TKobe UniversityThis study determined the predictive accuracy of optical frequency domain imaging (OFDI) on debulking effects of rotational atherectomy (RA) and compared the predictive accuracy of OFDI catheter-based with Rota wire-based prediction methods. This prospective, single-center, observational study included 55 consecutive patients who underwent OFDI-guided RA. On pre-RA OFDI images, a circle, identical to the Rota burr was drawn at the center of the OFDI catheter (OFDI catheter-based prediction method) or wire (wire-based prediction method). The area overlapping the vessel wall was defined as the predicted ablation area (P-area). The actual ablated area (A-area) was measured by superimposing the OFDI images before and after RA. The overlapping P-area and A-area were defined as overlapped ablatiCardiovascular intervention and therapeutics316-326https://www.ebi.ac.uk/biostudies/studies/S-EPMC10247835biostudies-literaturePrediction of the debulking effect of rotational atherectomy using optical frequency domain imaging: a prospective study.PMC10247835Nakamura KNaniwa SYamamoto TSasaki SFujii MOsumi YKawamori HHamana TToba TSakamoto YTanimura KFujimoto DHirata KIMatsuhama KNishimori MFukuishi YOtake HKakizaki SIwane SfalsePrediction of the debulking effect of rotational atherectomy using optical frequency domain imaging: a prospective study.This study determined the predictive accuracy of optical frequency domain imaging (OFDI) on debulking effects of rotational atherectomy (RA) and compared the predictive accuracy of OFDI catheter-based with Rota wire-based prediction methods. This prospective, single-center, observational study included 55 consecutive patients who underwent OFDI-guided RA. On pre-RA OFDI images, a circle, identical to the Rota burr was drawn at the center of the OFDI catheter (OFDI catheter-based prediction method) or wire (wire-based prediction method). The area overlapping the vessel wall was defined as the predicted ablation area (P-area). The actual ablated area (A-area) was measured by superimposing the OFDI images before and after RA. The overlapping P-area and A-area were defined as overlapped ablati2023-01-01T00:00:00Z2023 Jul2025-04-19T08:11:05.048Z2025-04-19T08:11:05.048ZS-EPMC102478353702006610.1007/s12928-023-00928-9