biostudies-literatureJohannessen ONHLBI NIH HHS2155-2165https://www.ebi.ac.uk/biostudies/studies/S-EPMC10247843biostudies-literatureUnknown38(10)Left atrial (LA) inflow propagation velocity from the pulmonary vein (LAIF-PV) has been proposed as a novel measure of LA reservoir function and is associated with pulmonary capillary wedge pressure in critically ill patients. However, data on LAIF-PV in acute heart failure (AHF) are lacking. We sought to examine the feasibility of measuring LAIF-PV and evaluate clinical and echocardiographic correlates of LAIF-PV in AHF. In a prospective cohort study of adults hospitalized for AHF, we used color M-mode Doppler of the pulmonary veins to obtain LAIF-PV in systole. Among 142 patients with appropriate images and no more than moderate mitral regurgitation, LAIF-PV measures were feasible in 76 patients (54%) aged 71 ± 14 years, including 68% men with left ventricular ejection fraction (LVEF) 38The international journal of cardiovascular imagingLeft atrial inflow propagation velocity derived by color M-mode Doppler in acute heart failure.PMC10247843K23HL123533Cheng SLewis EFRivero JMyhre PLLindner MClaggett BPlatz EJohannessen OfalseLeft atrial inflow propagation velocity derived by color M-mode Doppler in acute heart failure.Left atrial (LA) inflow propagation velocity from the pulmonary vein (LAIF-PV) has been proposed as a novel measure of LA reservoir function and is associated with pulmonary capillary wedge pressure in critically ill patients. However, data on LAIF-PV in acute heart failure (AHF) are lacking. We sought to examine the feasibility of measuring LAIF-PV and evaluate clinical and echocardiographic correlates of LAIF-PV in AHF. In a prospective cohort study of adults hospitalized for AHF, we used color M-mode Doppler of the pulmonary veins to obtain LAIF-PV in systole. Among 142 patients with appropriate images and no more than moderate mitral regurgitation, LAIF-PV measures were feasible in 76 patients (54%) aged 71 ± 14 years, including 68% men with left ventricular ejection fraction (LVEF) 382022-01-01T00:00:00Z2022 Oct2025-04-04T11:53:50.833Z2025-04-04T11:53:50.833ZS-EPMC102478433772645610.1007/s10554-022-02614-y