{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang W"],"funding":["Faculty of Science, Cairo University","U.S. Department of Agriculture","Science and Technology Program of Guizhou Province","National Natural Science Foundation of China","Chongqing Normal University","National Institute of Food and Agriculture","National Key Research and Development Program of China","Institute of Food and Agricultural Sciences, University of Florida"],"pagination":["1-16"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10248801"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["48"],"pubmed_abstract":["<h4>Introduction</h4>Odorant-binding proteins (OBPs) are a class of small molecular weight soluble proteins that exist as expanded gene families in all insects, acting as ligand carriers mediating olfaction and other physiological processes. During fungal infection, a subset of insect OBPs were shown to be differentially expressed.<h4>Objectives</h4>We tested whether the altered expression of insect OBPs during pathogenic infection plays a role in behavioral or immune interactions between insect hosts and their pathogens.<h4>Methods</h4>A wide range of techniques including RNAi-directed knockdown, heterologous protein expression, electrophysiological/behavioral analyses, transcriptomics, gut microbiome analyses, coupled with tandem mass spectrometry ion monitoring, were used to characteriz"],"journal":["Journal of advanced research"],"pubmed_title":["An odorant binding protein is involved in counteracting detection-avoidance and Toll-pathway innate immunity."],"pmcid":["PMC10248801"],"funding_grant_id":["2019-05150","32111530121","32001961","2017YFD0201208","32160666","31540089"],"pubmed_authors":["Zhang W","Keyhani NO","Xia Y","Zang LS","Song B","Jia C","Mohamed A","Cao Y","Xie M","Eleftherianos I","Bian J"],"additional_accession":[]},"is_claimable":false,"name":"An odorant binding protein is involved in counteracting detection-avoidance and Toll-pathway innate immunity.","description":"<h4>Introduction</h4>Odorant-binding proteins (OBPs) are a class of small molecular weight soluble proteins that exist as expanded gene families in all insects, acting as ligand carriers mediating olfaction and other physiological processes. During fungal infection, a subset of insect OBPs were shown to be differentially expressed.<h4>Objectives</h4>We tested whether the altered expression of insect OBPs during pathogenic infection plays a role in behavioral or immune interactions between insect hosts and their pathogens.<h4>Methods</h4>A wide range of techniques including RNAi-directed knockdown, heterologous protein expression, electrophysiological/behavioral analyses, transcriptomics, gut microbiome analyses, coupled with tandem mass spectrometry ion monitoring, were used to characteriz","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jun","modification":"2025-04-27T02:24:09.082Z","creation":"2025-04-06T18:31:36.414Z"},"accession":"S-EPMC10248801","cross_references":{"pubmed":["36064181"],"doi":["10.1016/j.jare.2022.08.013"]}}