{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Liu CT"],"pubmed_abstract":["Backgrounds
Early detection might help in reducing the burden and promoting the survival rate of gastric cancers. Herein, we tried to explore the diagnostic value of insulin-like growth factor binding protein 7 (IGFBP7) in gastric cancers.Methods
In this study, we first analyzed the expression levels and prognostic value of IGFBP7 mRNA in gastric cancers from The Cancer Genome Atlas (TCGA) database. Then, we recruited 169 gastric cancer patients and 100 normal controls as training cohort, and 55 gastric cancer patients and 55 normal controls as independent validation cohort. Enzyme-linked immunosorbent assay was applied to test the serum levels of IGFBP7. The receiver operating characteristic curve (ROC) and the area under the curve (AUC) were applied to evaluation the diag"],"journal":["PeerJ"],"pagination":["e15419"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10249617"],"repository":["biostudies-literature"],"pubmed_title":["The diagnostic value of serum insulin-like growth factor binding protein 7 in gastric cancer."],"pmcid":["PMC10249617"],"pubmed_authors":["Wu FC","Chen SL","Liu CT","Huang XY","Qu QQ","Peng YH","Zhuang YX","Li XH","Xu YW","Huang XC"],"additional_accession":[]},"is_claimable":false,"name":"The diagnostic value of serum insulin-like growth factor binding protein 7 in gastric cancer.","description":"Backgrounds
Early detection might help in reducing the burden and promoting the survival rate of gastric cancers. Herein, we tried to explore the diagnostic value of insulin-like growth factor binding protein 7 (IGFBP7) in gastric cancers.Methods
In this study, we first analyzed the expression levels and prognostic value of IGFBP7 mRNA in gastric cancers from The Cancer Genome Atlas (TCGA) database. Then, we recruited 169 gastric cancer patients and 100 normal controls as training cohort, and 55 gastric cancer patients and 55 normal controls as independent validation cohort. Enzyme-linked immunosorbent assay was applied to test the serum levels of IGFBP7. The receiver operating characteristic curve (ROC) and the area under the curve (AUC) were applied to evaluation the diag","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-27T02:17:51.137Z","creation":"2025-04-06T18:30:21.032Z"},"accession":"S-EPMC10249617","cross_references":{"pubmed":["37304887"],"doi":["10.7717/peerj.15419"]}}