biostudies-literatureLu GNational Natural Science Foundation of ChinaThe National Natural Science Foundation of ChinaFundamental Research Funds for the Central Universities, Southwest Minzu UniversityFoundation from Science and Technology Department of Sichuan Province1757https://www.ebi.ac.uk/biostudies/studies/S-EPMC10252012biostudies-literatureUnknown13(11)The presence or absence of subcutaneous adipose accumulation will affect the energy storage, insulation resistance and metabolism of animals. Proliferation and differentiation of preadipocytes play a significant role in lipid deposition. The objective of this study was to clone the goat <i>CXCL17</i> gene and investigate its potential functions on goat subcutaneous preadipocytes' proliferation by gaining or losing function in vitro. The goat <i>CXCL17</i> gene was cloned by Reverse Transcription-Polymerase Chain Reaction (RT-PCR) and bioinformatics analysis was performed. The expression of the <i>CXCL17</i> gene in the different goat tissues and adipocytes at different differentiation stages was detected by real-time fluorescence quantitative PCR (qPCR). The results showed that the cloned Animals : an open access journal from MDPIEffect of <i>CXCL17</i> on Subcutaneous Preadipocytes Proliferation in Goats.PMC1025201220210572022NSFSC006782002817Li YLu GMa XWang FLin YWang YChen DLiu WfalseEffect of <i>CXCL17</i> on Subcutaneous Preadipocytes Proliferation in Goats.The presence or absence of subcutaneous adipose accumulation will affect the energy storage, insulation resistance and metabolism of animals. Proliferation and differentiation of preadipocytes play a significant role in lipid deposition. The objective of this study was to clone the goat <i>CXCL17</i> gene and investigate its potential functions on goat subcutaneous preadipocytes' proliferation by gaining or losing function in vitro. The goat <i>CXCL17</i> gene was cloned by Reverse Transcription-Polymerase Chain Reaction (RT-PCR) and bioinformatics analysis was performed. The expression of the <i>CXCL17</i> gene in the different goat tissues and adipocytes at different differentiation stages was detected by real-time fluorescence quantitative PCR (qPCR). The results showed that the cloned 2023-01-01T00:00:00Z2023 May2026-04-08T13:11:01.62Z2025-04-04T03:42:25.598ZS-EPMC102520123788966410.3390/ani13111757