biostudies-literatureUnknown9(23)Liu FHere, we report a conceptual strategy for introducing spatial sulfur (S)-bridge ligands to regulate the coordination environment of Fe-Co-N dual-metal centers (Spa-S-Fe,Co/NC). Benefiting from the electronic modulation, Spa-S-Fe,Co/NC catalyst showed remarkably enhanced oxygen reduction reaction (ORR) performance with a half-wave potential (<i>E</i>_1/2) of 0.846 V and satisfactory long-term durability in acidic electrolyte. Combined experimental and theoretical studies revealed that the excellent acidic ORR activity with a remarkable stability observed for Spa-S-Fe,Co/NC is attributable to the optimal adsorption-desorption of ORR oxygenated intermediates achieved through charge-modulation of Fe-Co-N bimetallic centers by the spatial S-bridge ligands. These findings provide a uniScience advanceseadg0366https://www.ebi.ac.uk/biostudies/studies/S-EPMC10256161biostudies-literatureFe/Co dual metal catalysts modulated by S-ligands for efficient acidic oxygen reduction in PEMFC.PMC10256161Qiu JShi LHu CDai LLong YCheng RLin XYe FYan RLiu DZhang BLiu FfalseFe/Co dual metal catalysts modulated by S-ligands for efficient acidic oxygen reduction in PEMFC.Here, we report a conceptual strategy for introducing spatial sulfur (S)-bridge ligands to regulate the coordination environment of Fe-Co-N dual-metal centers (Spa-S-Fe,Co/NC). Benefiting from the electronic modulation, Spa-S-Fe,Co/NC catalyst showed remarkably enhanced oxygen reduction reaction (ORR) performance with a half-wave potential (<i>E</i>_1/2) of 0.846 V and satisfactory long-term durability in acidic electrolyte. Combined experimental and theoretical studies revealed that the excellent acidic ORR activity with a remarkable stability observed for Spa-S-Fe,Co/NC is attributable to the optimal adsorption-desorption of ORR oxygenated intermediates achieved through charge-modulation of Fe-Co-N bimetallic centers by the spatial S-bridge ligands. These findings provide a uni2023-01-01T00:00:00Z2023 Jun2025-04-19T03:37:31.559Z2025-04-07T13:44:32.418ZS-EPMC102561613729476310.1126/sciadv.adg0366