biostudies-literatureUnknown18(6)Selvaganesan KMagnetic resonance imaging (MRI) is a powerful noninvasive diagnostic tool with superior soft tissue contrast. However, access to MRI is limited since current systems depend on homogeneous, high field strength main magnets (B0-fields), with strong switchable gradients which are expensive to install and maintain. In this work we propose a new approach to MRI where imaging is performed in an inhomogeneous field using radiofrequency spatial encoding, thereby eliminating the need for uniform B0-fields and conventional cylindrical gradient coils. The proposed technology uses an innovative data acquisition and reconstruction approach by integrating developments in field cycling, parallel imaging and non-Fourier based algebraic reconstruction. The scanner uses field cycling to image in an inhomogPloS onee0287344https://www.ebi.ac.uk/biostudies/studies/S-EPMC10270621biostudies-literatureMagnetic resonance imaging using a nonuniform Bo (NuBo) field-cycling magnet.PMC10270621Ha YGaliana GConstable RTSelvaganesan KWu BWan YHancock KfalseMagnetic resonance imaging using a nonuniform Bo (NuBo) field-cycling magnet.Magnetic resonance imaging (MRI) is a powerful noninvasive diagnostic tool with superior soft tissue contrast. However, access to MRI is limited since current systems depend on homogeneous, high field strength main magnets (B0-fields), with strong switchable gradients which are expensive to install and maintain. In this work we propose a new approach to MRI where imaging is performed in an inhomogeneous field using radiofrequency spatial encoding, thereby eliminating the need for uniform B0-fields and conventional cylindrical gradient coils. The proposed technology uses an innovative data acquisition and reconstruction approach by integrating developments in field cycling, parallel imaging and non-Fourier based algebraic reconstruction. The scanner uses field cycling to image in an inhomog2023-01-01T00:00:00Z20232025-04-18T20:35:31.711Z2025-04-07T08:26:30.698ZS-EPMC102706213731928910.1371/journal.pone.0287344