{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liu J"],"funding":["National High Level Hospital Clinical Research Funding","Beijing Municipal Science & Technology Commission","CAMS Innovation Fund for Medical Sciences","National Natural Science Foundation of China","National Key Research and Development Program of China","Beijing Natural Science Foundation"],"pagination":["519-531"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10270746"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(6)"],"pubmed_abstract":["<h4>Background</h4>Glucokinase maturity-onset diabetes of the young (GCK-MODY) is difficult to distinguish from other diabetic forms. This article aims to characterize the differences in results from routine examinations between GCK-MODY and hepatocyte nuclear factor 1-α (HNF1A)-MODY or type 2 diabetes (T2D) patients in different periods of diabetes.<h4>Methods</h4>Ovid Medline, Embase, and the Cochrane Library were searched up until October 9, 2022 for articles containing baseline characteristics of GCK-MODY, HNF1A-MOFY, and T2D, excluding pregnant women. The pooled standardized mean differences were derived using a random-effects model.<h4>Results</h4>Compared to HNF1A-MODY, GCK-MODY patients had lower indicators of glucose metabolism. Total triglycerides (TG) (-0.93 [-1.66, -0.21] mmol/"],"journal":["Journal of diabetes"],"pubmed_title":["Insights from basic adjunctive examinations of GCK-MODY, HNF1A-MODY, and type 2 diabetes: A systemic review and meta-analysis."],"pmcid":["PMC10270746"],"funding_grant_id":["2018YFC2001100","2022-PUMCH-B-121","82170854","CIFMS2017-I2M-1-008","7202163","81570715","CIFMS2021-1-I2M-002","81170736","Z201100005520011","2022-PUMCH-C-019","81870545","81870579"],"pubmed_authors":["Liu J","Yu M","Xiao X","Zhang Q"],"additional_accession":[]},"is_claimable":false,"name":"Insights from basic adjunctive examinations of GCK-MODY, HNF1A-MODY, and type 2 diabetes: A systemic review and meta-analysis.","description":"<h4>Background</h4>Glucokinase maturity-onset diabetes of the young (GCK-MODY) is difficult to distinguish from other diabetic forms. This article aims to characterize the differences in results from routine examinations between GCK-MODY and hepatocyte nuclear factor 1-α (HNF1A)-MODY or type 2 diabetes (T2D) patients in different periods of diabetes.<h4>Methods</h4>Ovid Medline, Embase, and the Cochrane Library were searched up until October 9, 2022 for articles containing baseline characteristics of GCK-MODY, HNF1A-MOFY, and T2D, excluding pregnant women. The pooled standardized mean differences were derived using a random-effects model.<h4>Results</h4>Compared to HNF1A-MODY, GCK-MODY patients had lower indicators of glucose metabolism. Total triglycerides (TG) (-0.93 [-1.66, -0.21] mmol/","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jun","modification":"2025-04-22T18:52:44.384Z","creation":"2025-04-06T02:33:59.539Z"},"accession":"S-EPMC10270746","cross_references":{"pubmed":["37226652"],"doi":["10.1111/1753-0407.13390"]}}