biostudies-literatureLiu JNational High Level Hospital Clinical Research FundingBeijing Municipal Science & Technology CommissionCAMS Innovation Fund for Medical SciencesNational Natural Science Foundation of ChinaNational Key Research and Development Program of ChinaBeijing Natural Science Foundation519-531https://www.ebi.ac.uk/biostudies/studies/S-EPMC10270746biostudies-literatureUnknown15(6)<h4>Background</h4>Glucokinase maturity-onset diabetes of the young (GCK-MODY) is difficult to distinguish from other diabetic forms. This article aims to characterize the differences in results from routine examinations between GCK-MODY and hepatocyte nuclear factor 1-α (HNF1A)-MODY or type 2 diabetes (T2D) patients in different periods of diabetes.<h4>Methods</h4>Ovid Medline, Embase, and the Cochrane Library were searched up until October 9, 2022 for articles containing baseline characteristics of GCK-MODY, HNF1A-MOFY, and T2D, excluding pregnant women. The pooled standardized mean differences were derived using a random-effects model.<h4>Results</h4>Compared to HNF1A-MODY, GCK-MODY patients had lower indicators of glucose metabolism. Total triglycerides (TG) (-0.93 [-1.66, -0.21] mmol/Journal of diabetesInsights from basic adjunctive examinations of GCK-MODY, HNF1A-MODY, and type 2 diabetes: A systemic review and meta-analysis.PMC102707462018YFC20011002022-PUMCH-B-12182170854CIFMS2017-I2M-1-008720216381570715CIFMS2021-1-I2M-00281170736Z2011000055200112022-PUMCH-C-0198187054581870579Liu JYu MXiao XZhang QfalseInsights from basic adjunctive examinations of GCK-MODY, HNF1A-MODY, and type 2 diabetes: A systemic review and meta-analysis.<h4>Background</h4>Glucokinase maturity-onset diabetes of the young (GCK-MODY) is difficult to distinguish from other diabetic forms. This article aims to characterize the differences in results from routine examinations between GCK-MODY and hepatocyte nuclear factor 1-α (HNF1A)-MODY or type 2 diabetes (T2D) patients in different periods of diabetes.<h4>Methods</h4>Ovid Medline, Embase, and the Cochrane Library were searched up until October 9, 2022 for articles containing baseline characteristics of GCK-MODY, HNF1A-MOFY, and T2D, excluding pregnant women. The pooled standardized mean differences were derived using a random-effects model.<h4>Results</h4>Compared to HNF1A-MODY, GCK-MODY patients had lower indicators of glucose metabolism. Total triglycerides (TG) (-0.93 [-1.66, -0.21] mmol/2023-01-01T00:00:00Z2023 Jun2025-04-22T18:52:44.384Z2025-04-06T02:33:59.539ZS-EPMC102707463722665210.1111/1753-0407.13390