biostudies-literatureUnknown11(7)Madrid L<h4>Background</h4>Neural tube defects are common birth defects resulting in severe morbidity and mortality; they can largely be prevented with periconceptional maternal intake of folic acid. Understanding the occurrence of neural tube defects and their contribution to mortality in settings where their burden is highest could inform prevention and health-care policy. We aimed to estimate the mortality attributed to neural tube defects in seven countries in sub-Saharan Africa and southeast Asia.<h4>Methods</h4>This analysis used data from the Child Health and Mortality Prevention Surveillance (CHAMPS) network and health and demographic surveillance systems from South Africa, Mozambique, Bangladesh, Kenya, Mali, Ethiopia, and Sierra Leone. All stillbirths and infants and children younger thaThe Lancet. Global healthe1041-e1052https://www.ebi.ac.uk/biostudies/studies/S-EPMC10282076biostudies-literatureNeural tube defects as a cause of death among stillbirths, infants, and children younger than 5 years in sub-Saharan Africa and southeast Asia: an analysis of the CHAMPS network.PMC10282076Xerinda EOrlien SMBassey IASolomon FSanogo DOmore RDufera TSuchdev PSManhique ZChitungo DSorour GNhampossa TAhmed DTennant SMTilahun YMadhi SANhacolo AAkelo VGarel MFlora MSAlkis-Ramirez RGary JTippet-Barr BAKotloff KLRevathi GWaller JLKowuor DLeulseged HHossain MZBassat QMarami DMahtab SSalzberg NTMonjane CAlam MVaro RMutevedzi PCain CJFayorsey RKosia BLemma ECHAMPS ConsortiumSannoh SVerani JRChawana RBelachew ASwart PJVyas KJShirin TNhachungue SKancherla VTasnim SAbayneh Gizaw MMitei PKMaixenchs MDludlu NMocumbi SLuke RVitorino PMenendez CChowdhury MAIScott JAGSissoko SOnwuchekwa UGetnet FMehta AKeita AMGure TBlau DHoque MLee KHIbrahim AMNyamthimba PAcham YCarrilho CRitter JMWhitney CGNtuli CLala SGLako SEl Arifeen SWise AMoosa RHale MIgunza AKaluma EMekonnen AFairchild KDSesay FRahman AJohnson JKTraore AKindcardett MMandomando IKourouma NKoplan JPBari SMunguambe KWinchell JMNawshad Uddin Ahmed ASMTesfaye TSidibe DRahman MMurila FOgbuanu IGurley ESFernandes FAdam YBegum FWale HOrdi JVelaphi SIslam FZaman KPratt SBramugy JAjanovic SWitherbee JAlemu AIslam KMOele ELiu LKoka RValente MPetersen KGreene CLOundo JONair STapia MDWadula JSow SOKone DRakislova NAssefa NParveen SMadrid LKeita TEdris YSamura SHurtado JCFritz AFentaw SOnyango DPass Philipsborn RMoses FKamal MMosiur MRogena ETemesgen FArjuman FAhmed MSZaki SRDewey BOnwuchekwa UUKhan IAKuria MLombaard HYeshi MMfalseNeural tube defects as a cause of death among stillbirths, infants, and children younger than 5 years in sub-Saharan Africa and southeast Asia: an analysis of the CHAMPS network.<h4>Background</h4>Neural tube defects are common birth defects resulting in severe morbidity and mortality; they can largely be prevented with periconceptional maternal intake of folic acid. Understanding the occurrence of neural tube defects and their contribution to mortality in settings where their burden is highest could inform prevention and health-care policy. We aimed to estimate the mortality attributed to neural tube defects in seven countries in sub-Saharan Africa and southeast Asia.<h4>Methods</h4>This analysis used data from the Child Health and Mortality Prevention Surveillance (CHAMPS) network and health and demographic surveillance systems from South Africa, Mozambique, Bangladesh, Kenya, Mali, Ethiopia, and Sierra Leone. All stillbirths and infants and children younger tha2023-01-01T00:00:00Z2023 Jul2025-04-05T12:14:05.557Z2024-11-13T21:29:32.853ZS-EPMC102820763727116210.1016/S2214-109X(23)00191-2