biostudies-literatureUnknown18(6)Hsueh CM<h4>Purpose</h4>Identify risk factors of progression in treated normal-tension glaucoma (NTG) in highly myopic and non-highly myopic eyes.<h4>Methods</h4>This retrospective, observational case series study included 42 highly myopic glaucoma (HMG, <-6D) eyes and 39 non-highly myopic glaucoma (NHG,≧-6D) eyes. Glaucoma progression was determined by serial visual field data. Univariate and multivariate logistic regression method were used to detect associations between potential risk factors and glaucoma progression.<h4>Results</h4>Among 81 eyes from 81 normal-tension glaucoma patients (mean follow-up, 3.10 years), 20 of 42 eye (45.24%) in the HMG and 14 of 39 eyes (35.90%) in the NHG showed progression. The HMG group had larger optic disc tilt ratio (p = 0.007) and thinner inferior macular thPloS onee0287661https://www.ebi.ac.uk/biostudies/studies/S-EPMC10289344biostudies-literatureEffect of myopia on the progression of normal tension glaucoma.PMC10289344Yeh JSHsueh CMHo JDfalseEffect of myopia on the progression of normal tension glaucoma.<h4>Purpose</h4>Identify risk factors of progression in treated normal-tension glaucoma (NTG) in highly myopic and non-highly myopic eyes.<h4>Methods</h4>This retrospective, observational case series study included 42 highly myopic glaucoma (HMG, <-6D) eyes and 39 non-highly myopic glaucoma (NHG,≧-6D) eyes. Glaucoma progression was determined by serial visual field data. Univariate and multivariate logistic regression method were used to detect associations between potential risk factors and glaucoma progression.<h4>Results</h4>Among 81 eyes from 81 normal-tension glaucoma patients (mean follow-up, 3.10 years), 20 of 42 eye (45.24%) in the HMG and 14 of 39 eyes (35.90%) in the NHG showed progression. The HMG group had larger optic disc tilt ratio (p = 0.007) and thinner inferior macular th2023-01-01T00:00:00Z20232025-04-04T18:42:38.194Z2025-04-04T18:42:38.194ZS-EPMC102893443735229110.1371/journal.pone.0287661