{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Yang P"],"pubmed_abstract":["<h4>Background</h4>Preoperative prediction of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) may optimize individualized treatment decision-making. This study aimed to investigate the prognostic differences between HCC patients undergoing liver resection (LR) and liver transplantation (LT) based on predicted MVI risks.<h4>Methods</h4>We analysed 905 patients who underwent LR, including 524 who underwent anatomical resection (AR) and 117 who underwent LT for HCC within the Milan criteria using propensity score matching. A nomogram model was used to predict preoperative MVI risk.<h4>Results</h4>The concordance indices of the nomogram for predicting MVI were 0.809 and 0.838 in patients undergoing LR and LT, respectively. Based on an optimal cut-off value of 200 points, the nom"],"journal":["Gastroenterology report"],"pagination":["goad035"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10293589"],"repository":["biostudies-literature"],"pubmed_title":["Liver resection versus liver transplantation for hepatocellular carcinoma within the Milan criteria based on estimated microvascular invasion risks."],"pmcid":["PMC10293589"],"pubmed_authors":["Xia Y","Li J","Xie Z","Fu Z","Teng F","Wan X","Shen H","Wang K","Cheng Z","Pawlik TM","Shen F","Yin H","Bai S","Lei Z","Yang P","Yang T","Zhang B","Lau WY"],"additional_accession":[]},"is_claimable":false,"name":"Liver resection versus liver transplantation for hepatocellular carcinoma within the Milan criteria based on estimated microvascular invasion risks.","description":"<h4>Background</h4>Preoperative prediction of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) may optimize individualized treatment decision-making. This study aimed to investigate the prognostic differences between HCC patients undergoing liver resection (LR) and liver transplantation (LT) based on predicted MVI risks.<h4>Methods</h4>We analysed 905 patients who underwent LR, including 524 who underwent anatomical resection (AR) and 117 who underwent LT for HCC within the Milan criteria using propensity score matching. A nomogram model was used to predict preoperative MVI risk.<h4>Results</h4>The concordance indices of the nomogram for predicting MVI were 0.809 and 0.838 in patients undergoing LR and LT, respectively. Based on an optimal cut-off value of 200 points, the nom","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-22T09:46:12.15Z","creation":"2025-04-05T23:17:17.744Z"},"accession":"S-EPMC10293589","cross_references":{"pubmed":["37384119"],"doi":["10.1093/gastro/goad035"]}}