biostudies-literatureUnknown23(1)Nie G<h4>Background</h4>Hyperuricemia and sarcopenia are both strongly linked to an increased risk of atherosclerotic cardiovascular disease (ASCVD), and this study was designed to look into the interactive effects of hyperuricemia on ASCVD risk.<h4>Methods</h4>This study collected information from patients (N = 2647) who underwent health check-ups at the Health Care Building of Wuhan Union Hospital between January 2019 and December 2020. Skeletal muscle mass was measured using bioelectrical impedance methods. The Asian Working Group on Sarcopenia diagnostic criteria were used to classify patients with sarcopenia. ASCVD risk was calculated using the Framingham Heart Study, and ASCVD risk ≥ 20% was considered high risk ASCVD. IBM SPSS 25.0 and GraphPad prism 8.0 software were used for data analyBMC cardiovascular disorders325https://www.ebi.ac.uk/biostudies/studies/S-EPMC10294447biostudies-literatureAssociation of hyperuricemia combined with sarcopenia on ASCVD risk.PMC10294447Jiang LPeng WWan JZhang MNie GYan FfalseAssociation of hyperuricemia combined with sarcopenia on ASCVD risk.<h4>Background</h4>Hyperuricemia and sarcopenia are both strongly linked to an increased risk of atherosclerotic cardiovascular disease (ASCVD), and this study was designed to look into the interactive effects of hyperuricemia on ASCVD risk.<h4>Methods</h4>This study collected information from patients (N = 2647) who underwent health check-ups at the Health Care Building of Wuhan Union Hospital between January 2019 and December 2020. Skeletal muscle mass was measured using bioelectrical impedance methods. The Asian Working Group on Sarcopenia diagnostic criteria were used to classify patients with sarcopenia. ASCVD risk was calculated using the Framingham Heart Study, and ASCVD risk ≥ 20% was considered high risk ASCVD. IBM SPSS 25.0 and GraphPad prism 8.0 software were used for data analy2023-01-01T00:00:00Z2023 Jun2025-04-19T08:59:41.875Z2025-04-19T08:59:41.875ZS-EPMC102944473737001210.1186/s12872-023-03336-2