{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gomes RMODS"],"funding":["Coordenação de Aperfeicoamento de Pessoal de Nível Superior","National Council for Scientific and Technological Development"],"pagination":["629"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10299519"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(6)"],"pubmed_abstract":["The species complexes <i>Cryptococcus neoformans</i> and <i>Cryptococcus gattii</i> are the causative agents of cryptococcosis. Virulence and susceptibility to antifungals may vary within each species according to the fungal genotype. Therefore, specific and easily accessible molecular markers are required to distinguish cryptic species and/or genotypes. Group I introns are potential markers for this purpose because they are polymorphic concerning their presence and sequence. Therefore, in this study, we evaluated the presence of group I introns in the mitochondrial genes <i>cob</i> and <i>cox1</i> in different <i>Cryptococcus</i> isolates. Additionally, the origin, distribution, and evolution of these introns were investigated by phylogenetic analyses, including previously sequenced intro"],"journal":["Journal of fungi (Basel, Switzerland)"],"pubmed_title":["Distribution and Polymorphisms of Group I Introns in Mitochondrial Genes from <i>Cryptococcus neoformans</i> and <i>Cryptococcus gattii</i>."],"pmcid":["PMC10299519"],"funding_grant_id":["Fellowship","401513/2016-5","305506/2019-6"],"pubmed_authors":["Ferreira LC","Arantes TD","Gomes RMODS","Theodoro RC","da Silva KJG"],"additional_accession":[]},"is_claimable":false,"name":"Distribution and Polymorphisms of Group I Introns in Mitochondrial Genes from <i>Cryptococcus neoformans</i> and <i>Cryptococcus gattii</i>.","description":"The species complexes <i>Cryptococcus neoformans</i> and <i>Cryptococcus gattii</i> are the causative agents of cryptococcosis. Virulence and susceptibility to antifungals may vary within each species according to the fungal genotype. Therefore, specific and easily accessible molecular markers are required to distinguish cryptic species and/or genotypes. Group I introns are potential markers for this purpose because they are polymorphic concerning their presence and sequence. Therefore, in this study, we evaluated the presence of group I introns in the mitochondrial genes <i>cob</i> and <i>cox1</i> in different <i>Cryptococcus</i> isolates. Additionally, the origin, distribution, and evolution of these introns were investigated by phylogenetic analyses, including previously sequenced intro","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-18T17:27:22.119Z","creation":"2025-04-07T04:58:37.469Z"},"accession":"S-EPMC10299519","cross_references":{"pubmed":["37367565"],"doi":["10.3390/jof9060629"]}}