{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mahjour B"],"funding":["ACS MEDI Predoctoral Fellowship","National Science Foundation"],"pagination":["3924"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10318092"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["High-throughput experimentation (HTE) is an increasingly important tool in reaction discovery. While the hardware for running HTE in the chemical laboratory has evolved significantly in recent years, there remains a need for software solutions to navigate data-rich experiments. Here we have developed phactor™, a software that facilitates the performance and analysis of HTE in a chemical laboratory. phactor™ allows experimentalists to rapidly design arrays of chemical reactions or direct-to-biology experiments in 24, 96, 384, or 1,536 wellplates. Users can access online reagent data, such as a chemical inventory, to virtually populate wells with experiments and produce instructions to perform the reaction array manually, or with the assistance of a liquid handling robot. After completion of"],"journal":["Nature communications"],"pubmed_title":["Rapid planning and analysis of high-throughput experiment arrays for reaction discovery."],"pmcid":["PMC10318092"],"funding_grant_id":["CHE-2236215"],"pubmed_authors":["Mohamed OG","Douthwaite JL","Cernak T","Zhao R","Zhang Z","Lin Y","Tripathi A","Mahjour B","Shen Y","McGrath A","Zhang R"],"additional_accession":[]},"is_claimable":false,"name":"Rapid planning and analysis of high-throughput experiment arrays for reaction discovery.","description":"High-throughput experimentation (HTE) is an increasingly important tool in reaction discovery. While the hardware for running HTE in the chemical laboratory has evolved significantly in recent years, there remains a need for software solutions to navigate data-rich experiments. Here we have developed phactor™, a software that facilitates the performance and analysis of HTE in a chemical laboratory. phactor™ allows experimentalists to rapidly design arrays of chemical reactions or direct-to-biology experiments in 24, 96, 384, or 1,536 wellplates. Users can access online reagent data, such as a chemical inventory, to virtually populate wells with experiments and produce instructions to perform the reaction array manually, or with the assistance of a liquid handling robot. After completion of","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jul","modification":"2025-04-18T17:51:00.306Z","creation":"2025-04-07T05:25:05.267Z"},"accession":"S-EPMC10318092","cross_references":{"pubmed":["37400469"],"doi":["10.1038/s41467-023-39531-0"]}}