{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang Y"],"funding":["Shanghai Hospital Development Center","Shanghai Public Health System’s Talent Development Plan","Science and Technology Commission of Shanghai Municipality","Star Program of Shanghai Jiaotong University","Shanghai Hospital Development Center (SHDC)","National Natural Science Foundation of China","Science and Technology Commission of Shanghai Municipality (Shanghai Municipal Science and Technology Commission)","National Natural Science Foundation of China (National Science Foundation of China)"],"pagination":["2048-2054"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10333345"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["37(10)"],"pubmed_abstract":["<h4>Purpose</h4>To investigate the growth of nonexudative macular neovascularization (MNV) in age-related macular degeneration (AMD) using swept-source optical coherence tomography angiography (SS-OCTA).<h4>Methods</h4>Patients with treatment-naïve nonexudative AMD in one eye and exudative AMD in the fellow eye who underwent SS-OCTA imaging for at least 12 months were retrospectively reviewed. The MNV area measurement was quantified in eyes with treatment-naïve nonexudative MNV using ImageJ for analysing the correlation between MNV growth and the onset of exudation, as well as evaluating the consistency of the MNV growth rate during the subclinical and exudative stages. Kaplan-Meier survival analysis and logistic regression analyses were used.<h4>Results</h4>In total, 45 eyes with treatmen"],"journal":["Eye (London, England)"],"pubmed_title":["Growth of nonexudative macular neovascularization in age-related macular degeneration: an indicator of biological lesion activity."],"pmcid":["PMC10333345"],"funding_grant_id":["SHDC2020CR2040B","82171076","SHDC2020CR5014","20Z11900400"],"pubmed_authors":["Wu J","Bo Q","Feng J","Yan Q","Chen J","Jia H","Wang F","Wang Y","Sun X","Sun J","Huang P"],"additional_accession":[]},"is_claimable":false,"name":"Growth of nonexudative macular neovascularization in age-related macular degeneration: an indicator of biological lesion activity.","description":"<h4>Purpose</h4>To investigate the growth of nonexudative macular neovascularization (MNV) in age-related macular degeneration (AMD) using swept-source optical coherence tomography angiography (SS-OCTA).<h4>Methods</h4>Patients with treatment-naïve nonexudative AMD in one eye and exudative AMD in the fellow eye who underwent SS-OCTA imaging for at least 12 months were retrospectively reviewed. The MNV area measurement was quantified in eyes with treatment-naïve nonexudative MNV using ImageJ for analysing the correlation between MNV growth and the onset of exudation, as well as evaluating the consistency of the MNV growth rate during the subclinical and exudative stages. Kaplan-Meier survival analysis and logistic regression analyses were used.<h4>Results</h4>In total, 45 eyes with treatmen","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jul","modification":"2025-04-26T15:10:56.448Z","creation":"2025-04-06T14:51:14.762Z"},"accession":"S-EPMC10333345","cross_references":{"pubmed":["36434285"],"doi":["10.1038/s41433-022-02282-1"]}}