{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["23(1)"],"submitter":["Dolmaci OB"],"pubmed_abstract":["<h4>Introduction</h4>Bicuspid aortic valve (BAV) patients have an increased risk to develop thoracic aortic complications. Little is known about the prevalence and severity of atherosclerosis in the BAV ascending aortic wall. This study evaluates and compares the prevalence of thoracic aortic atherosclerosis in BAV and tricuspid aortic valve (TAV) patients.<h4>Methods</h4>Atherosclerosis was objectified using three diagnostic modalities in two separate BAV patient cohorts (with and without an aortic dilatation). Within the first group, atherosclerosis was graded histopathologically according to the modified AHA classification scheme proposed by Virmani et al. In the second group, the calcific load of the ascending aorta and coronary arteries, coronary angiographies and cardiovascular risk "],"journal":["BMC cardiovascular disorders"],"pagination":["363"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10355074"],"repository":["biostudies-literature"],"pubmed_title":["Thoracic aortic atherosclerosis in patients with a bicuspid aortic valve; a case-control study."],"pmcid":["PMC10355074"],"pubmed_authors":["Sprengers R","Dolmaci OB","Poelmann RE","Klautz RJM","Kroft L","Grewal N","Lindeman JHN"],"additional_accession":[]},"is_claimable":false,"name":"Thoracic aortic atherosclerosis in patients with a bicuspid aortic valve; a case-control study.","description":"<h4>Introduction</h4>Bicuspid aortic valve (BAV) patients have an increased risk to develop thoracic aortic complications. Little is known about the prevalence and severity of atherosclerosis in the BAV ascending aortic wall. This study evaluates and compares the prevalence of thoracic aortic atherosclerosis in BAV and tricuspid aortic valve (TAV) patients.<h4>Methods</h4>Atherosclerosis was objectified using three diagnostic modalities in two separate BAV patient cohorts (with and without an aortic dilatation). Within the first group, atherosclerosis was graded histopathologically according to the modified AHA classification scheme proposed by Virmani et al. In the second group, the calcific load of the ascending aorta and coronary arteries, coronary angiographies and cardiovascular risk ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jul","modification":"2025-05-29T20:49:24.861Z","creation":"2025-05-29T20:49:24.861Z"},"accession":"S-EPMC10355074","cross_references":{"pubmed":["37468858"],"doi":["10.1186/s12872-023-03396-4"]}}