biostudies-literatureRoss JMNCI NIH HHSofad330https://www.ebi.ac.uk/biostudies/studies/S-EPMC10358428biostudies-literatureUnknown10(7)<h4>Background</h4>Over 870 000 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have occurred among Veterans Health Administration users, and 24 000 have resulted in death. We examined early outcomes of SARS-CoV-2 infection in hospitalized veterans.<h4>Methods</h4>In an ongoing, prospective cohort study, we enrolled veterans age ≥18 tested for SARS-CoV-2 and hospitalized at 15 Department of Veterans Affairs medical centers between February 2021 and June 2022. We estimated adjusted odds ratios (aORs), adjusted incidence rate ratios (aIRRs), and adjusted hazard ratios (aHRs) for maximum illness severity within 30 days of study entry (defined using the 4-category VA Severity Index for coronavirus disease 2019 [COVID-19]), as well as length of hospitalization and rehospOpen forum infectious diseasesEarly Outcomes of SARS-CoV-2 Infection in a Multisite Prospective Cohort of Inpatient Veterans.PMC10358428K08 CA228761Katzel LGundacker MNWang GJones BELee JSPaintal MHChang KMSugimoto JDWoods CWan EEastment MKorpak ALewis JDanaher PMcClain MEPIC InvestigatorsManaktala RCoffey KHaque MJCrothers KMahatme SAnzueto ADeardoff KVittor ARoghmann MCStevenson MTheus JSmith NLCho KShah JAPowers PLe EPerez FHolodniy MHunt CMPfeiffer CGarshick ETimmons ANicholson LJump RAdams JMoore KRoss JMWilson DIsaacs SNBaker JLiu CGaziano JMArkansas NBedimo RfalseEarly Outcomes of SARS-CoV-2 Infection in a Multisite Prospective Cohort of Inpatient Veterans.<h4>Background</h4>Over 870 000 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have occurred among Veterans Health Administration users, and 24 000 have resulted in death. We examined early outcomes of SARS-CoV-2 infection in hospitalized veterans.<h4>Methods</h4>In an ongoing, prospective cohort study, we enrolled veterans age ≥18 tested for SARS-CoV-2 and hospitalized at 15 Department of Veterans Affairs medical centers between February 2021 and June 2022. We estimated adjusted odds ratios (aORs), adjusted incidence rate ratios (aIRRs), and adjusted hazard ratios (aHRs) for maximum illness severity within 30 days of study entry (defined using the 4-category VA Severity Index for coronavirus disease 2019 [COVID-19]), as well as length of hospitalization and rehosp2023-01-01T00:00:00Z2023 Jul2025-06-01T01:38:56.972Z2025-06-01T01:38:56.972ZS-EPMC103584283748489910.1093/ofid/ofad330