{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["SCORE2-Diabetes Working Group and the ESC Cardiovascular Risk Collaboration"],"funding":["Kidney Research UK","GlaxoSmithKline","British Heart Foundation","British United Provident Association (BUPA) Foundation","National Institute for Health and Care Research (NIHR) Cambridge Biomedical Research Centre","Medical Research Council","National Institute for Health Research (NIHR)","Chief Scientist Office","Wellcome Trust","BHF Centre of Research Excellence"],"pagination":["2544-2556"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10361012"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["44(28)"],"pubmed_abstract":["<h4>Aims</h4>To develop and validate a recalibrated prediction model (SCORE2-Diabetes) to estimate the 10-year risk of cardiovascular disease (CVD) in individuals with type 2 diabetes in Europe.<h4>Methods and results</h4>SCORE2-Diabetes was developed by extending SCORE2 algorithms using individual-participant data from four large-scale datasets comprising 229 460 participants (43 706 CVD events) with type 2 diabetes and without previous CVD. Sex-specific competing risk-adjusted models were used including conventional risk factors (i.e. age, smoking, systolic blood pressure, total, and HDL-cholesterol), as well as diabetes-related variables (i.e. age at diabetes diagnosis, glycated haemoglobin [HbA1c] and creatinine-based estimated glomerular filtration rate [eGFR]). Models were recalibrat"],"journal":["European heart journal"],"pubmed_title":["SCORE2-Diabetes: 10-year cardiovascular risk estimation in type 2 diabetes in Europe."],"pmcid":["PMC10361012"],"funding_grant_id":["NIHR203312","JFDKcsf2/2017","RE/18/1/34212","SP/09/002","RG/18/13/33946","NIHR203769","HDR-9004","HDR-9005","MR/L003120/1","RG/13/13/30194","SP/18/3/33801","MC_UU_00017/3","MR/R007764/1","BRC-1215–20014"],"pubmed_authors":["Willeit J","Volzke H","Willeit P","Stocker H","Azzopardi J","Rossing P","SCORE2-Diabetes Working Group and the ESC Cardiovascular Risk Collaboration","Vardas P","Hageman SHJ","Eliasson B","Du Y","Notdurfter M","Taylor O","Kaptoge S","Vlacho B","Taylor J","Poljicanin T","Prieto-Merino D","Heidemann C","Lavens A","Gillum RF","Gall T","Graham I","Walker MR","Holman N","Buble T","Visseren FLJ","Tilg H","Fumeron F","Urbancic-Rovan V","Magri CJ","Holleczek B","Kiechl S","Halle M","Mauricio D","Di Angelantonio E","Lawlor DA","Sascha R","Benedetti MM","Brenner H","Xu Z","Leitner C","Franch-Nadal J","Timmis A","Real J","Vistisen D","Schmidt CO","Dorr M","Herrington W","Stotl I","Mata-Cases M","Ference B","Sattar N","Pennells L","Carinci F","Balkau B","Sofat R","Danesh J","Ivanko P","Bonnet F","De Bacquer D","Sandor J","Janos S","Scheidt-Nave C","Vanherwegen AS","Dorresteijn JAN","Baltane Z","Pildava S","Read SH","Gualdi S","Schipf S","Lepiksone J","Tibor G","Pristas I","Dale C","Wood A","Carstensen B","Wild S","Petitjean C","Huculeci R","Potier L","Schottker B","Shi F","Fava S","McEvoy JW","Da Providencia E Costa RB","Ostergaard HB","Spackman S"],"additional_accession":[]},"is_claimable":false,"name":"SCORE2-Diabetes: 10-year cardiovascular risk estimation in type 2 diabetes in Europe.","description":"<h4>Aims</h4>To develop and validate a recalibrated prediction model (SCORE2-Diabetes) to estimate the 10-year risk of cardiovascular disease (CVD) in individuals with type 2 diabetes in Europe.<h4>Methods and results</h4>SCORE2-Diabetes was developed by extending SCORE2 algorithms using individual-participant data from four large-scale datasets comprising 229 460 participants (43 706 CVD events) with type 2 diabetes and without previous CVD. Sex-specific competing risk-adjusted models were used including conventional risk factors (i.e. age, smoking, systolic blood pressure, total, and HDL-cholesterol), as well as diabetes-related variables (i.e. age at diabetes diagnosis, glycated haemoglobin [HbA1c] and creatinine-based estimated glomerular filtration rate [eGFR]). Models were recalibrat","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jul","modification":"2026-06-17T06:45:21.944Z","creation":"2026-06-17T03:07:58.21Z"},"accession":"S-EPMC10361012","cross_references":{"pubmed":["37247330"],"doi":["10.1093/eurheartj/ehad260"]}}