{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Gu X"],"pubmed_abstract":["Recurrent heat stress and pathogen invasion seriously threaten crop production, and abiotic stress often antagonizes biotic stress response against pathogens. However, the molecular mechanisms of trade-offs between thermotolerance and defense remain obscure. Here, we identify a rice thermo-sensitive mutant that displays a defect in floret development under high temperature with a mutation in SUPPRESSOR OF GENE SILENCING 3a (OsSGS3a). OsSGS3a interacts with its homolog OsSGS3b and modulates the biogenesis of trans-acting small interfering RNA (tasiRNA) targeting AUXIN RESPONSE FACTORS (ARFs). We find that OsSGS3a/b positively, while OsARF3a/b and OsARF3la/lb negatively modulate thermotolerance. Moreover, OsSGS3a negatively, while OsARF3a/b and OsARF3la/lb positively regulate disease resista"],"journal":["Nature communications"],"pagination":["4441"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10366173"],"repository":["biostudies-literature"],"pubmed_title":["The OsSGS3-tasiRNA-OsARF3 module orchestrates abiotic-biotic stress response trade-off in rice."],"pmcid":["PMC10366173"],"pubmed_authors":["Liu J","Li J","Gu X","Feng Z","Wu XN","Yang C","Li L","Zhao Z","Liang D","Tang J","Feng L","Yang Y","Li S","Cao X","Li T","He Z","Yang P","Wan J","Liu JY","Si F","Yan B","Song X","Zhou J","Deng Y"],"additional_accession":[]},"is_claimable":false,"name":"The OsSGS3-tasiRNA-OsARF3 module orchestrates abiotic-biotic stress response trade-off in rice.","description":"Recurrent heat stress and pathogen invasion seriously threaten crop production, and abiotic stress often antagonizes biotic stress response against pathogens. However, the molecular mechanisms of trade-offs between thermotolerance and defense remain obscure. Here, we identify a rice thermo-sensitive mutant that displays a defect in floret development under high temperature with a mutation in SUPPRESSOR OF GENE SILENCING 3a (OsSGS3a). OsSGS3a interacts with its homolog OsSGS3b and modulates the biogenesis of trans-acting small interfering RNA (tasiRNA) targeting AUXIN RESPONSE FACTORS (ARFs). We find that OsSGS3a/b positively, while OsARF3a/b and OsARF3la/lb negatively modulate thermotolerance. Moreover, OsSGS3a negatively, while OsARF3a/b and OsARF3la/lb positively regulate disease resista","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jul","modification":"2025-04-05T12:34:19.221Z","creation":"2025-04-05T12:34:19.221Z"},"accession":"S-EPMC10366173","cross_references":{"pubmed":["37488129"],"doi":["10.1038/s41467-023-40176-2"]}}