biostudies-literatureNilsen MNorges Forskningsråde0078923https://www.ebi.ac.uk/biostudies/studies/S-EPMC10370313biostudies-literatureUnknown89(7)Bacteroides and Phocaeicola, members of the family <i>Bacteroidaceae</i>, are among the first microbes to colonize the human infant gut. While it is known that these microbes can be transmitted from mother to child, our understanding of the specific strains that are shared and potentially transmitted is limited. In this study, we aimed to investigate the shared strains of Bacteroides and Phocaeicola in mothers and their infants. We analyzed fecal samples from pregnant woman recruited at 18 weeks of gestation from the PreventADALL study, as well as offspring samples from early infancy, including skin swab samples taken within 10 min after birth, the first available fecal sample (meconium), and fecal samples at 3 months of age. We screened 464 meconium samples for <i>Bacteroidaceae</i>, withApplied and environmental microbiologyA Globally Distributed Bacteroides caccae Strain Is the Most Prevalent Mother-Child Shared <i>Bacteroidaceae</i> Strain in a Large Scandinavian Cohort.PMC10370313301364Hedlin GNilsen MSnipen LStaff ACNordlund BHaugen GSoderhall CLodrup Carlsen KCSkjerven HOJonassen CMOrmaasen IRehbinder EMWilborn LMKillingstad MEVettukattil RRudi KSorensen RfalseA Globally Distributed Bacteroides caccae Strain Is the Most Prevalent Mother-Child Shared <i>Bacteroidaceae</i> Strain in a Large Scandinavian Cohort.Bacteroides and Phocaeicola, members of the family <i>Bacteroidaceae</i>, are among the first microbes to colonize the human infant gut. While it is known that these microbes can be transmitted from mother to child, our understanding of the specific strains that are shared and potentially transmitted is limited. In this study, we aimed to investigate the shared strains of Bacteroides and Phocaeicola in mothers and their infants. We analyzed fecal samples from pregnant woman recruited at 18 weeks of gestation from the PreventADALL study, as well as offspring samples from early infancy, including skin swab samples taken within 10 min after birth, the first available fecal sample (meconium), and fecal samples at 3 months of age. We screened 464 meconium samples for <i>Bacteroidaceae</i>, with2023-01-01T00:00:00Z2023 Jul2026-06-11T06:38:39.424Z2025-04-06T02:55:32.779ZS-EPMC103703133733837910.1128/aem.00789-23