{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Huai B"],"funding":["the Natural Foundation of Guangdong Province","Open Competition Program of Ten Major Directions of Agricultural Science and Technology Innovation for the 14th Five-Year Plan of Guangdong Province","National Natural Science Foundation of China","key Realm R&amp;amp;D Program of Guangdong Province","Natural Foundation of Guangdong Province","the Open Competition Program of Ten Major Directions of Agricultural Science and Technology Innovation for the 14th Five-Year Plan of Guangdong Province","the National Natural Science Foundation of China","key Realm R&D Program of Guangdong Province"],"pagination":["11681"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10380461"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(14)"],"pubmed_abstract":["Vacuolar processing enzymes (VPEs) with caspase-1-like activity are closely associated with vacuole rupture. The destruction of vacuoles is one of the characteristics of programmed cell death (PCD) in plants. However, whether VPE is involved in the vacuole destruction of cells during secretory cavity formation in <i>Citrus</i> plants remains unclear. This research identified a <i>CgVPE1</i> gene that encoded the VPE and utilized cytology and molecular biology techniques to explore its temporal and spatial expression characteristics during the PCD process of secretory cavity cells in the <i>Citrus grandis</i> 'Tomentosa' fruit. The results showed that CgVPE1 is an enzyme with VPE and caspase-1-like activity that can self-cleave into a mature enzyme in an acidic environment. <i>CgVPE1</i> is"],"journal":["International journal of molecular sciences"],"pubmed_title":["Involvement of Vacuolar Processing Enzyme CgVPE1 in Vacuole Rupture in the Programmed Cell Death during the Development of the Secretory Cavity in <i>Citrus grandis</i> 'Tomentosa' Fruits."],"pmcid":["PMC10380461"],"funding_grant_id":["2020B020221001","31870172","2022A1515010795","2022SDZG07"],"pubmed_authors":["Tong P","Liang X","Chen J","He H","Bai M","Liang M","Lin J","Huai B","Wu H"],"additional_accession":[]},"is_claimable":false,"name":"Involvement of Vacuolar Processing Enzyme CgVPE1 in Vacuole Rupture in the Programmed Cell Death during the Development of the Secretory Cavity in <i>Citrus grandis</i> 'Tomentosa' Fruits.","description":"Vacuolar processing enzymes (VPEs) with caspase-1-like activity are closely associated with vacuole rupture. The destruction of vacuoles is one of the characteristics of programmed cell death (PCD) in plants. However, whether VPE is involved in the vacuole destruction of cells during secretory cavity formation in <i>Citrus</i> plants remains unclear. This research identified a <i>CgVPE1</i> gene that encoded the VPE and utilized cytology and molecular biology techniques to explore its temporal and spatial expression characteristics during the PCD process of secretory cavity cells in the <i>Citrus grandis</i> 'Tomentosa' fruit. The results showed that CgVPE1 is an enzyme with VPE and caspase-1-like activity that can self-cleave into a mature enzyme in an acidic environment. <i>CgVPE1</i> is","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jul","modification":"2026-06-21T03:15:48.728Z","creation":"2025-04-20T03:16:10.221Z"},"accession":"S-EPMC10380461","cross_references":{"pubmed":["37511439"],"doi":["10.3390/ijms241411681"]}}