{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lecona AM"],"funding":["Consejo Nacional de Ciencia y Tecnología","National Autonomous University of Mexico","CONACyT","DGAPA/PAPIIT-UNAM"],"pagination":["11720"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10380779"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(14)"],"pubmed_abstract":["Cysteine-rich receptor-like kinases (CRKs) are a type of receptor-like kinases (RLKs) that are important for pathogen resistance, extracellular reactive oxygen species (ROS) signaling, and programmed cell death in plants. In a previous study, we identified 46 CRK family members in the <i>Phaseolus vulgaris</i> genome and found that <i>CRK12</i> was highly upregulated under root nodule symbiotic conditions. To better understand the role of <i>CRK12</i> in the <i>Phaseolus</i>-<i>Rhizobia</i> symbiotic interaction, we functionally characterized this gene by overexpressing (<i>CRK12</i>-OE) and silencing (<i>CRK12</i>-RNAi) it in a <i>P. vulgaris</i> hairy root system. We found that the constitutive expression of <i>CRK12</i> led to an increase in root hair length and the expression of root h"],"journal":["International journal of molecular sciences"],"pubmed_title":["<i>CRK12</i>: A Key Player in Regulating the <i>Phaseolus vulgaris</i>-<i>Rhizobium tropici</i> Symbiotic Interaction."],"pmcid":["PMC10380779"],"funding_grant_id":["CF-MI-20191017134234199-316538","IN216321 and IN213221","IN216321","IN213221"],"pubmed_authors":["Lecona AM","Nanjareddy K","Vera-Nunez JA","Piazza V","Lara M","Blanco L","Arthikala MK"],"additional_accession":[]},"is_claimable":false,"name":"<i>CRK12</i>: A Key Player in Regulating the <i>Phaseolus vulgaris</i>-<i>Rhizobium tropici</i> Symbiotic Interaction.","description":"Cysteine-rich receptor-like kinases (CRKs) are a type of receptor-like kinases (RLKs) that are important for pathogen resistance, extracellular reactive oxygen species (ROS) signaling, and programmed cell death in plants. In a previous study, we identified 46 CRK family members in the <i>Phaseolus vulgaris</i> genome and found that <i>CRK12</i> was highly upregulated under root nodule symbiotic conditions. To better understand the role of <i>CRK12</i> in the <i>Phaseolus</i>-<i>Rhizobia</i> symbiotic interaction, we functionally characterized this gene by overexpressing (<i>CRK12</i>-OE) and silencing (<i>CRK12</i>-RNAi) it in a <i>P. vulgaris</i> hairy root system. We found that the constitutive expression of <i>CRK12</i> led to an increase in root hair length and the expression of root h","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jul","modification":"2025-07-04T03:06:01.15Z","creation":"2025-02-19T03:56:13.994Z"},"accession":"S-EPMC10380779","cross_references":{"pubmed":["37511479"],"doi":["10.3390/ijms241411720"]}}