biostudies-literatureWang Ythe 67th batch of China Postdoctoral Science FoundationScience and Technology Projects of Yunnan Province5480https://www.ebi.ac.uk/biostudies/studies/S-EPMC10384535biostudies-literatureUnknown28(14)<i>Anneslea fragrans</i> Wall., popularly known as "Pangpo tea", is an edible, medicinal, and ornamental plant of the Family Theaceae. The leaves of <i>A. fragrans</i> were historically applied for the treatment of liver and intestinal inflammatory diseases in China. This study aimed to explore the hepatoprotective agents from <i>A. fragrans</i> leaves through hepatoprotective and anti-inflammatory assessment. The phytochemical investigation of the leaves of <i>A. fragrans</i> resulted in the isolation and identification of a total of 18 chemical compounds, including triterpenoids, aliphatic alcohol, dihydrochalcones, chalcones, flavanols, phenolic glycoside, and lignans. Compounds <b>1</b>-<b>2</b>, <b>4</b>-<b>6</b>, <b>11</b>-<b>12</b>, and <b>16</b>-<b>18</b> were identified from <i>A.Molecules (Basel, Switzerland)Phytochemicals from <i>Anneslea fragrans</i> Wall. and Their Hepatoprotective and Anti-Inflammatory Activities.PMC103845352020M673586XB2019ZF010Cheng CLiu YCao JZhou WZhao TWang YCheng GfalsePhytochemicals from <i>Anneslea fragrans</i> Wall. and Their Hepatoprotective and Anti-Inflammatory Activities.<i>Anneslea fragrans</i> Wall., popularly known as "Pangpo tea", is an edible, medicinal, and ornamental plant of the Family Theaceae. The leaves of <i>A. fragrans</i> were historically applied for the treatment of liver and intestinal inflammatory diseases in China. This study aimed to explore the hepatoprotective agents from <i>A. fragrans</i> leaves through hepatoprotective and anti-inflammatory assessment. The phytochemical investigation of the leaves of <i>A. fragrans</i> resulted in the isolation and identification of a total of 18 chemical compounds, including triterpenoids, aliphatic alcohol, dihydrochalcones, chalcones, flavanols, phenolic glycoside, and lignans. Compounds <b>1</b>-<b>2</b>, <b>4</b>-<b>6</b>, <b>11</b>-<b>12</b>, and <b>16</b>-<b>18</b> were identified from <i>A.2023-01-01T00:00:00Z2023 Jul2025-04-21T17:07:14.902Z2025-04-21T17:07:14.902ZS-EPMC103845353751335210.3390/molecules28145480