{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(30)"],"submitter":["Murata T"],"pubmed_abstract":["The first total synthesis of (+)-tanzawaic acid B, a natural polyketide bearing a pentadienoic ester and octalin moiety, has been accomplished. The synthetic improvement from previous synthetic conditions facilitated our gram-scale synthesis of the chiral octalin that possesses seven stereogenic centers and that is the core skeleton of almost all of the tanzawaic acid family."],"journal":["ACS omega"],"pagination":["27703-27709"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10399178"],"repository":["biostudies-literature"],"pubmed_title":["First Total Synthesis of Tanzawaic Acid B."],"pmcid":["PMC10399178"],"pubmed_authors":["Hiraishi S","Shiina I","Natsukawa H","Tsutsui H","Tateyama S","Takano A","Yoshida T","Suzuki K","Maekawa Y","Umezaki Y","Shibata N","Inohana T","Murata T","Kubota H","Sato T","Toyoyama K","Ito K","Egashira N","Yonekura K","Honda M","Tasaki Y","Suzuki Y","Mori T","Hiraga D"],"additional_accession":[]},"is_claimable":false,"name":"First Total Synthesis of Tanzawaic Acid B.","description":"The first total synthesis of (+)-tanzawaic acid B, a natural polyketide bearing a pentadienoic ester and octalin moiety, has been accomplished. The synthetic improvement from previous synthetic conditions facilitated our gram-scale synthesis of the chiral octalin that possesses seven stereogenic centers and that is the core skeleton of almost all of the tanzawaic acid family.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Aug","modification":"2025-04-05T00:24:03.636Z","creation":"2025-04-05T00:24:03.636Z"},"accession":"S-EPMC10399178","cross_references":{"pubmed":["37546667"],"doi":["10.1021/acsomega.3c03634"]}}